Deep learning techniques for detecting freezing of gait episodes in Parkinson's disease using wearable sensors.

IF 3.2 3区 医学 Q2 PHYSIOLOGY
Frontiers in Physiology Pub Date : 2025-05-01 eCollection Date: 2025-01-01 DOI:10.3389/fphys.2025.1581699
Mosleh Hmoud Al-Adhaileh, Asim Wadood, Theyazn H H Aldhyani, Safeer Khan, M Irfan Uddin, Abdullah H Al-Nefaie
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引用次数: 0

Abstract

Freezing of Gait (FoG) is a disabling motor symptom that characterizes Parkinson's Disease (PD) patients and significantly affects their mobility and quality of life. The paper presents a novel hybrid deep learning framework for the detection of FoG episodes using wearable sensors. The methodology combines CNNs for spatial feature extraction, BiLSTM networks for temporal modeling, and an attention mechanism to enhance interpretability and focus on critical gait features. The approach leverages multimodal datasets, including tDCS FOG, DeFOG, Daily Living, and Hantao's Multimodal, to ensure robustness and generalizability. The proposed model deals with sensor noise, inter-subject variability, and data imbalance through comprehensive preprocessing techniques such as sensor fusion, normalization, and data augmentation. The proposed model achieved an average accuracy of 92.5%, F1-score of 89.3%, and AUC of 0.91, outperforming state-of-the-art methods. Post-training quantization and pruning enabled deployment on edge devices such as Raspberry Pi and Coral TPU, achieving inference latency under 350 ms. Ablation studies show the critical contribution of key architectural components to the model's effectiveness. Optimized to be deployed real-time, it is a potentially promising solution that can help correctly detect FoG, thereby achieving better clinical monitoring and improving patients' outcomes in a controlled as well as real world.

使用可穿戴传感器检测帕金森病步态冻结的深度学习技术。
步态冻结(FoG)是帕金森病(PD)患者的一种致残性运动症状,严重影响其活动能力和生活质量。本文提出了一种新的混合深度学习框架,用于使用可穿戴传感器检测FoG事件。该方法将cnn用于空间特征提取,BiLSTM网络用于时间建模,并结合注意机制来增强可解释性并关注关键步态特征。该方法利用多模式数据集,包括tDCS FOG、DeFOG、Daily Living和汉涛的multimodal,以确保鲁棒性和泛化性。该模型通过传感器融合、归一化和数据增强等综合预处理技术处理传感器噪声、学科间变异性和数据不平衡等问题。该模型的平均准确率为92.5%,f1得分为89.3%,AUC为0.91,优于目前最先进的方法。训练后量化和修剪可以部署在边缘设备上,如树莓派和珊瑚TPU,实现350毫秒以下的推理延迟。消融研究显示了关键建筑构件对模型有效性的重要贡献。优化后可以实时部署,这是一个潜在的有前途的解决方案,可以帮助正确检测FoG,从而实现更好的临床监测,改善患者在受控和现实世界中的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.50
自引率
5.00%
发文量
2608
审稿时长
14 weeks
期刊介绍: Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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