Case Report: Extrapulmonary tuberculosis presenting as multiple caseous pericardial masses.

IF 2.8 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Frontiers in Cardiovascular Medicine Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI:10.3389/fcvm.2025.1529400
Juan Wang, Run Zhang, Zhengliang Li, Hui Fang, Wenzhong Zhang
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Abstract

The diagnosis of tuberculous pericarditis presenting as a hemorrhagic pericardial effusion is not difficult to make, but the presence of multiple pericardial masses in tuberculous pericarditis is uncommon. The article reports a 55-year-old Asian woman with a 10-day history of fever, chest tightness and shortness of breath. Laboratory investigations revealed an elevated C-reactive protein and erythrocyte sedimentation rate, and echocardiography showed a small amount of pericardial effusion associated with multiple pericardial caseous masses (up to approximately 2.4 cm × 6.9 cm) without pericardial constriction. Ten ml of bloody pericardial effusion was punctured and sent for pathology without malignant cells, and malignant mesothelioma was excluded in combination with PET-CT results. The diagnosis of extrapulmonary tuberculosis was finally confirmed by a positive Mantoux test and positive tuberculosis immunoreactivity, and the patient is now receiving standardized anti-tuberculosis treatment in a specialist hospital. Nowadays, the diagnosis of tuberculous pericarditis is not difficult, but the symptoms of a concomitant giant mass are rare, and its nature and treatment options (including drugs or surgery) are worth exploring.

病例报告:肺外结核表现为多发干酪样心包包块。
结核性心包炎表现为出血性心包积液并不难诊断,但结核性心包炎中出现多发心包肿块并不常见。这篇文章报道了一名55岁的亚洲女性,她有10天的发烧、胸闷和呼吸短促的病史。实验室检查显示c反应蛋白和红细胞沉降率升高,超声心动图显示少量心包积液伴多发心包干酪样包块(约2.4 cm × 6.9 cm),无心包收缩。穿刺带血心包积液10ml,病理未见恶性细胞,结合PET-CT结果排除恶性间皮瘤。曼图试验阳性和结核免疫反应阳性最终证实了肺外结核的诊断,患者目前正在一家专科医院接受标准化的抗结核治疗。如今,结核性心包炎的诊断并不困难,但伴随巨大肿块的症状很少见,其性质和治疗方案(包括药物或手术)值得探索。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.80
自引率
11.10%
发文量
3529
审稿时长
14 weeks
期刊介绍: Frontiers? Which frontiers? Where exactly are the frontiers of cardiovascular medicine? And who should be defining these frontiers? At Frontiers in Cardiovascular Medicine we believe it is worth being curious to foresee and explore beyond the current frontiers. In other words, we would like, through the articles published by our community journal Frontiers in Cardiovascular Medicine, to anticipate the future of cardiovascular medicine, and thus better prevent cardiovascular disorders and improve therapeutic options and outcomes of our patients.
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