A Non-Negligible Role of Benign Paroxysmal Positional Vertigo in Paediatric Vertigo: A Systematic Review and Meta-Analysis

IF 1.5 4区医学 Q2 OTORHINOLARYNGOLOGY

Clinical Otolaryngology Pub Date : 2025-05-15 DOI:10.1111/coa.14323

Jing Zhang, Jing Guan, Hongyang Wang, Jiao Zhang, Dayong Wang, Dong Yang, Huifang Zhou, Qiuju Wang

{"title":"A Non-Negligible Role of Benign Paroxysmal Positional Vertigo in Paediatric Vertigo: A Systematic Review and Meta-Analysis","authors":"Jing Zhang, Jing Guan, Hongyang Wang, Jiao Zhang, Dayong Wang, Dong Yang, Huifang Zhou, Qiuju Wang","doi":"10.1111/coa.14323","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>Benign paroxysmal positional vertigo is a common cause of vertigo in adults but has been studied less extensively in children. Interestingly, the reported diagnostic frequency of benign paroxysmal positional vertigo in paediatric vertigo showed high variability. This systematic review and meta-analysis aimed to evaluate the proportion of benign paroxysmal positional vertigo in childhood vertigo and explore relevant factors to accurately diagnose BPPV in children.</p>\n </section>\n \n <section>\n \n <h3> Design</h3>\n \n <p>Systematic review and meta-analysis.</p>\n </section>\n \n <section>\n \n <h3> Setting and Participants</h3>\n \n <p>PubMed, EMBASE database and Cochrane library (from 1 January 1962, to 12 April 2022) were searched for eligible studies analysing the proportion of benign paroxysmal positional vertigo in children with vertigo. Only papers published in English were included.</p>\n </section>\n \n <section>\n \n <h3> Main Outcome Measures</h3>\n \n <p>The pooled proportion of paediatric BPPV in childhood vertigo, and its corresponding 95% confidence interval (CI), were calculated. Additional subgroup analysis was performed by year of publication, testing techniques, department, regions, age and registering comorbidities of relevance for balance.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Ultimately, 26 studies were eligible for our meta-analysis. These studies involved 4043 childhood vertigo cases, of which 460 were BPPV. Based on the results of a random-effects model-based meta-analysis, the pooled proportion of benign paroxysmal positional vertigo in childhood vertigo was 5.5%. However, a subgroup analysis revealed a significantly higher pooled proportion of benign paroxysmal positional vertigo, with 9.9% in the videonystagmography subgroup and 17.1% in the comorbidity subgroup. Moreover, the proportion of BPPV varies among children with vertigo in different age groups.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>In conclusion, the pooled proportion of BPPV in vertigo children was 5.5% across all samples. The present study revealed that age, applying VNG in positional testing, and comorbidity diagnosis may be closely related to the diagnosis of BPPV in children. Additionally, to prevent missed diagnosis of benign paroxysmal positional vertigo, diagnostic BPPV tests should not be neglected in children suffering from other vertigo-associated diseases.</p>\n </section>\n </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"50 5","pages":"808-820"},"PeriodicalIF":1.5000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Otolaryngology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/coa.14323","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

Benign paroxysmal positional vertigo is a common cause of vertigo in adults but has been studied less extensively in children. Interestingly, the reported diagnostic frequency of benign paroxysmal positional vertigo in paediatric vertigo showed high variability. This systematic review and meta-analysis aimed to evaluate the proportion of benign paroxysmal positional vertigo in childhood vertigo and explore relevant factors to accurately diagnose BPPV in children.

Design

Systematic review and meta-analysis.

Setting and Participants

PubMed, EMBASE database and Cochrane library (from 1 January 1962, to 12 April 2022) were searched for eligible studies analysing the proportion of benign paroxysmal positional vertigo in children with vertigo. Only papers published in English were included.

Main Outcome Measures

The pooled proportion of paediatric BPPV in childhood vertigo, and its corresponding 95% confidence interval (CI), were calculated. Additional subgroup analysis was performed by year of publication, testing techniques, department, regions, age and registering comorbidities of relevance for balance.

Results

Ultimately, 26 studies were eligible for our meta-analysis. These studies involved 4043 childhood vertigo cases, of which 460 were BPPV. Based on the results of a random-effects model-based meta-analysis, the pooled proportion of benign paroxysmal positional vertigo in childhood vertigo was 5.5%. However, a subgroup analysis revealed a significantly higher pooled proportion of benign paroxysmal positional vertigo, with 9.9% in the videonystagmography subgroup and 17.1% in the comorbidity subgroup. Moreover, the proportion of BPPV varies among children with vertigo in different age groups.

Conclusion

In conclusion, the pooled proportion of BPPV in vertigo children was 5.5% across all samples. The present study revealed that age, applying VNG in positional testing, and comorbidity diagnosis may be closely related to the diagnosis of BPPV in children. Additionally, to prevent missed diagnosis of benign paroxysmal positional vertigo, diagnostic BPPV tests should not be neglected in children suffering from other vertigo-associated diseases.

查看原文本刊更多论文

良性阵发性位置性眩晕在小儿眩晕中不可忽视的作用：系统回顾和荟萃分析。

目的：良性阵发性位置性眩晕是成人眩晕的常见原因，但对儿童的研究较少。有趣的是，报道的良性阵发性位置性眩晕在小儿眩晕中的诊断频率显示出很高的变异性。本系统回顾和荟萃分析旨在评估良性阵发性体位性眩晕在儿童眩晕中的比例，探讨准确诊断儿童BPPV的相关因素。设计：系统回顾和荟萃分析。环境和参与者：检索PubMed、EMBASE数据库和Cochrane图书馆（从1962年1月1日至2022年4月12日），寻找符合条件的研究，分析眩晕儿童良性阵发性位置性眩晕的比例。仅收录了以英文发表的论文。主要结局指标：计算小儿BPPV在儿童眩晕中的合并比例及其相应的95%置信区间（CI）。根据发表年份、检测技术、科室、地区、年龄和登记的合并症进行额外的亚组分析，以达到平衡。结果：最终有26项研究符合我们的荟萃分析。这些研究涉及4043例儿童眩晕病例，其中460例为BPPV。基于随机效应模型的meta分析结果显示，良性阵发性位置性眩晕在儿童眩晕中的合并比例为5.5%。然而，亚组分析显示良性阵发性位置性眩晕的总比例明显更高，其中视频震图亚组为9.9%，合并症亚组为17.1%。此外，在不同年龄组的眩晕患儿中，BPPV的比例也有所不同。结论：眩晕患儿中BPPV的合并比例为5.5%。本研究发现，年龄、应用VNG进行体位检查、合并症诊断可能与儿童BPPV的诊断密切相关。此外，为了防止对良性阵发性体位性眩晕的漏诊，在患有其他眩晕相关疾病的儿童中，诊断性BPPV测试不应被忽视。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.