Mental Health Consequences of Age-Related Macular Degeneration: Exploring Depression Prevalence and Severity in Wet and Dry Forms.

IF 2.6 3区医学 Q3 GERIATRICS & GERONTOLOGY

Clinical Gerontologist Pub Date : 2025-05-15 DOI:10.1080/07317115.2025.2506768

Nikolaos Gouliopoulos, Nikolaos Bouratzis, Stylianos Kympouropoulos, Ioannis Datseris, Ilias Georgalas, Panagiotis Theodossiadis, Alexandros Rouvas

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引用次数: 0

Abstract

Objectives: Age-related macular degeneration (AMD) is a leading cause of vision loss, affecting quality of life. Although AMD is associated with an increased risk of depression, differences between dry and wet forms are not well understood. This study examined depressive symptoms in Greek patients with dry and wet AMD compared to healthy-controls using the Zung Self-Rating Depression Scale (SDS).

Methods: A cross-sectional study included 146 AMD patients (74 dry, 72 wet) and 60 controls. Depressive symptoms were assessed using the Zung SDS. Demographic and clinical data were collected. Statistical analyses compared depression severity and prevalence between groups, adjusting for potential confounders.

Results: Wet AMD patients had significantly higher Zung SDS scores (50.4 ± 7.81) than dry AMD (44.8 ± 6.75) and controls (41.4 ± 7.85, p < .001). Depression prevalence was 56% in wet, 27% in dry AMD, and 20% in controls. After adjusting for visual acuity, age, sex, and other factors, wet AMD remained significantly associated with greater depression severity (p < .001).

Conclusions: Wet AMD is associated with higher depression severity compared to dry AMD, emphasizing the need for integrated ophthalmologic and mental health care.

Clinical implications: Depression is common among AMD patients, particularly those with wet AMD. Screening and psychological support should be incorporated into AMD management.

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年龄相关性黄斑变性的心理健康后果：探索抑郁症的患病率和严重程度在湿和干形式。

目的：年龄相关性黄斑变性（AMD）是视力丧失的主要原因，影响生活质量。虽然AMD与抑郁症风险增加有关，但干型和湿型之间的差异尚不清楚。本研究使用Zung抑郁自评量表（SDS）比较了希腊干性和湿性AMD患者与健康对照者的抑郁症状。方法：横断面研究纳入146例AMD患者（干性74例，湿性72例）和60例对照。使用Zung SDS评估抑郁症状。收集了人口统计学和临床数据。统计分析比较了各组之间抑郁症的严重程度和患病率，并对潜在的混杂因素进行了调整。结果：湿性AMD患者的Zung SDS评分（50.4±7.81）明显高于干性AMD（44.8±6.75）和对照组（41.4±7.85），p < 0.05。结论：湿性AMD与干性AMD的抑郁严重程度相关，强调了综合眼科和心理保健的必要性。临床意义：抑郁症在AMD患者中很常见，尤其是湿性AMD患者。AMD的治疗应纳入筛查和心理支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Gerontologist GERIATRICS & GERONTOLOGY-PSYCHIATRY

CiteScore

6.20

自引率

25.00%

发文量

审稿时长

>12 weeks

期刊介绍： Clinical Gerontologist presents original research, reviews, and clinical comments relevant to the needs of behavioral health professionals and all practitioners who work with older adults. Published in cooperation with Psychologists in Long Term Care, the journal is designed for psychologists, physicians, nurses, social workers, counselors (family, pastoral, and vocational), and other health professionals who address behavioral health concerns found in later life, including: -adjustments to changing roles- issues related to diversity and aging- family caregiving- spirituality- cognitive and psychosocial assessment- depression, anxiety, and PTSD- Alzheimer’s disease and other neurocognitive disorders- long term care- behavioral medicine in aging- rehabilitation and education for older adults. Each issue provides insightful articles on current topics. Submissions are peer reviewed by content experts and selected for both scholarship and relevance to the practitioner to ensure that the articles are among the best in the field. Authors report original research and conceptual reviews. A unique column in Clinical Gerontologist is “Clinical Comments." This section features brief observations and specific suggestions from practitioners which avoid elaborate research designs or long reference lists. This section is a unique opportunity for you to learn about the valuable clinical work of your peers in a short, concise format.