Green approach for the synthesis of zinc oxide nanoparticles and their enhanced sun protection factor in the presence of octocrylene.

IF 1.6 4区 医学 Q3 OPHTHALMOLOGY
M Pasupathi, S Moscow, B Natarajan, T Kumar
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引用次数: 0

Abstract

Background/purpose: This research project aims to create and test an eco-friendly method for producing zinc oxide nanoparticles (ZnO NPs) using herbal extracts. The goal is to study how these nanoparticles can boost the Sun Protection Factor (SPF) of sunscreens when used along with the synthetic UV filter octocrylene.

Methods: To make the ZnO NPs extracts from green tea, Bhringraj, Licorice and Cinnamon were used. These nanoparticles were analyzed using transmission electron microscopy (TEM). Sunscreen compositions were formulated as oil in water emulsions with or without octocrylene incorporating the ZnO NPs. Stability tests were carried out to monitor pH levels, colour and viscosity over the eight weeks at 45°C. The Sun Protection Factor study was done in vitro using a UV spectrophotometer.

Results: The results showed that formulations containing both ZnO NPs and octocrylene had SPF levels compared to using octocrylene or ZnO NPs alone. Around 1.4 to 1.65 times higher than octocrylene alone and 3.7 to 4.5 times higher than ZnO NPs alone. The stability study demonstrated changes in pH, viscosity and colour during storage. Conclusion: In conclusion eco-friendly production of ZnO NPs utilizing herbal extracts presents a sustainable alternative to traditional methods. When combined with octocrylene these nanoparticles significantly enhance the SPF of products.

Conclusion: In conclusion eco-friendly production of ZnO NPs utilizing herbal extracts presents a sustainable alternative to traditional methods. When combined with octocrylene these nanoparticles significantly enhance the SPF of products.This study introduces an eco-friendly approach, to creating high SPF sunscreens focusing on sustainability and addressing safety and environmental issues in sun care products. The rising demand for sunscreens has triggered the exploration of innovative methods for producing zinc oxide nanoparticles (ZnO NPs) that go beyond traditional chemical processes. The research exhibits a synthesis method for ZnO NPs using herbal extracts from green tea leaves, Bhringraj leaves, Liquorice roots and Cinnamon bark avoiding the use of harmful precursors. The results display dispersed ZnO NPs with an average size of 100 nm. Furthermore, the study investigates how these green synthesized ZnO NPs interact with the synthetic UV filter octocrylene to potentially enhance SPF in sunscreen formulations. By combining these components, the study shows an increase in SPF compared to using them individually.This study adds to the knowledge of how green synthesized ZnO NPs enhance efficacy of sunscreen products. This study also introduces an innovative approach, for creating eco-friendly effective sunscreens that could revolutionize sun protection methods.

绿色方法合成氧化锌纳米颗粒及其在八烯存在下增强的防晒系数。
背景/目的:本研究项目旨在创建和测试一种利用草药提取物生产氧化锌纳米颗粒(ZnO NPs)的环保方法。目的是研究这些纳米粒子如何在与合成紫外线过滤器八烯一起使用时提高防晒霜的防晒系数(SPF)。方法:以绿茶、甘草、桂皮为原料制备氧化锌NPs提取物。利用透射电子显微镜(TEM)对这些纳米颗粒进行了分析。防晒组合物被配制成含有或不含含有ZnO NPs的八烯的水乳液中的油。在45°C下进行了8周的稳定性测试,以监测pH值、颜色和粘度。防晒因子研究是用紫外分光光度计在体外完成的。结果:结果表明,与单独使用ZnO NPs或ZnO NPs相比,同时含有ZnO NPs和octocrylene的配方具有较高的SPF水平。比单独的八烯烯高1.4 ~ 1.65倍,比单独的ZnO NPs高3.7 ~ 4.5倍。稳定性研究表明,在储存过程中,pH值、粘度和颜色发生了变化。结论:利用草药提取物生产ZnO纳米粒子是一种可持续的替代方法。当与八烯烯结合时,这些纳米颗粒显着提高了产品的SPF。结论:利用草药提取物生产ZnO纳米粒子是一种可持续的替代方法。当与八烯烯结合时,这些纳米颗粒显着提高了产品的SPF。本研究介绍了一种环保的方法,以创造高SPF防晒霜,重点是可持续发展和解决防晒产品的安全和环境问题。对防晒霜不断增长的需求引发了对生产氧化锌纳米粒子(ZnO NPs)的创新方法的探索,这些方法超越了传统的化学工艺。本研究提出了一种利用绿茶叶、苦参叶、甘草根和肉桂皮的草药提取物合成ZnO NPs的方法,避免了使用有害的前体。结果显示ZnO纳米粒子分散,平均尺寸为100 nm。此外,该研究还研究了这些绿色合成ZnO NPs如何与合成紫外线过滤器八烯相互作用,以潜在地提高防晒霜配方中的SPF。研究表明,与单独使用这些成分相比,组合使用这些成分可以提高SPF值。这项研究增加了绿色合成氧化锌纳米粒子如何提高防晒产品功效的知识。这项研究还介绍了一种创新的方法,用于制造环保有效的防晒霜,这可能会彻底改变防晒方法。
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来源期刊
CiteScore
3.30
自引率
6.20%
发文量
40
审稿时长
1 months
期刊介绍: Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.
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