Preparation of self-healing pHEMA hydrogels using dynamic covalent crosslinkers

IF 2.8 4区工程技术 Q2 POLYMER SCIENCE

Macromolecular Research Pub Date : 2024-12-06 DOI:10.1007/s13233-024-00352-9

Jung-Hyun Choi, Byoung-Ki Cho

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引用次数: 0

Abstract

In this study, a crosslinker with dynamic properties (SH-Crosslinker) was synthesized via the thiol-Michael reaction and the introduction of methacrylate groups. A self-healing hydrogel (SH-Hydrogel) was then produced through the thermal polymerization of 2-hydroxyethyl methacrylate (HEMA) and SH-Crosslinker. In contrast to an unhealable control hydrogel prepared using ethylene glycol dimethacrylate (EGDMA) crosslinker, SH-Hydrogel demonstrated a recovery of nearly 90% of its original tensile strength after being cut. Utilizing the same solution mixture used in the SH-Hydrogel production, a self-healing contact lens (SH-Lens) was fabricated. This contact lens demonstrated a high visible-light transmittance of 97.3% and a water content of 40.4%, comparable to commercial contact lenses. Consequently, this research on hydrogels with dynamically crosslinked agents enabled the development of contact lenses with self-healing properties.

Graphical abstract

Self-healing poly(2-hydroxyethyl methacrylate) hydrogels based on dynamic covalent crosslinker.

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利用动态共价交联剂制备自愈pHEMA水凝胶

本研究通过巯基-迈克尔反应和引入甲基丙烯酸酯基团合成了一种具有动力学性能的交联剂（sh -交联剂）。然后通过甲基丙烯酸2-羟乙酯（HEMA）和sh -交联剂的热聚合制得自愈水凝胶（SH-Hydrogel）。与使用乙二醇二甲基丙烯酸酯（EGDMA）交联剂制备的不可修复水凝胶相比，sh -水凝胶在切割后的抗拉强度恢复了近90%。利用与sh -水凝胶生产相同的溶液混合物，制备了自修复隐形眼镜（SH-Lens）。该隐形眼镜的可见光透过率为97.3%，含水量为40.4%，与商用隐形眼镜相当。因此，对具有动态交联剂的水凝胶的研究使具有自愈特性的隐形眼镜的开发成为可能。图示：基于动态共价交联剂的自修复聚甲基丙烯酸羟乙酯水凝胶。

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来源期刊

Macromolecular Research 工程技术-高分子科学

CiteScore

4.70

自引率

8.30%

发文量

100

审稿时长

1.3 months

期刊介绍： Original research on all aspects of polymer science, engineering and technology, including nanotechnology Presents original research articles on all aspects of polymer science, engineering and technology Coverage extends to such topics as nanotechnology, biotechnology and information technology The English-language journal of the Polymer Society of Korea Macromolecular Research is a scientific journal published monthly by the Polymer Society of Korea. Macromolecular Research publishes original researches on all aspects of polymer science, engineering, and technology as well as new emerging technologies using polymeric materials including nanotechnology, biotechnology, and information technology in forms of Articles, Communications, Notes, Reviews, and Feature articles.