Synthetic strategies to pyrido fused heterocycles

Abstract

Pyridine fused heterocycles are vital in material sciences, medicinal chemistry, and organic synthesis due to their distinct structural feature. These compounds, consisting of two or more heterocyclic rings, share one or more hetero atoms. They exhibit enhanced stability, varied electronic properties, and improved biological activity compared to their non-fused counterparts. The fusion of heterocyclic rings often leads to a rigid, planar structure that can interact more efficiently with biological targets, making them valued in advancing pharmaceuticals, particularly for intricate diseases. Additionally, fused heterocycles are important in designing functional materials, such as organic semiconductors and catalysts, due to their ability to impart desired electronic and optical properties. Their broad pertinence and the ability to fine-tune their characteristics through synthetic modifications continue to drive advancements in basic and applied chemistry. The fused heterocycles discussed in this review are furo-pyridine, pyrrolo-pyridine, and other assorted fused heterocycles. Their biological importance and synthetic procedures have been discussed.

Graphical abstract

The fused heterocycles discussed are furo-pyridine, pyrrolo-pyridine, and other assorted fused heterocycles. The biological importance and synthetic procedures of these fused heterocycles have been discussed. Pyridine fused heterocycles are vital in material sciences, medicinal chemistry, and organic synthesis due to their distinct structural feature.