Neonatal lactobezoar (milk curd syndrome): a case report

IF 0.2 Q4 PEDIATRICS
Saswati Behera , Gulshan Kumar Saini , Ram Samujh , Navdeep Singh Dhoat , Manish Swami
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Abstract

Introduction

Lactobezoar or milk curd syndrome (MCS) is a rare cause of neonatal small bowel obstruction (SBO). Its incidence has decreased with the reduced use of formula rich in calcium and fat, but sporadic cases continued to be reported.

Case presentation

A full-term newborn with a birth weight of 3500 g was brought to the emergency room on day 26 of life due to respiratory distress and a two-day history of feeding intolerance, progressive abdominal distension and multiple episodes of bilious vomiting. The baby had primarily been fed cow's milk, along with intermittent formula. Following initial resuscitation in the intensive care unit, an abdominal x-ray was obtained, which showed dilated bowel loops, multiple air fluid levels, and ground glass appearance in right iliac fossa. He underwent an ultrasound (US) study of the abdomen which ruled out a midgut volvulus. The patient was taken to the operating room for an emergency laparotomy. We found clear ascites, a normal jejunum, and a severely dilated ileum and colon. The lumen of the ileum and colon was full of curd-like contents, or lactobezoars. The bowel wall also had pneumatosis intestinalis. The intraluminal contents were evacuated through gentle manual forward milking. No bowel resection was needed. The baby was started on broad-spectrum antibiotics covering both gram-negative and anaerobic organisms. The baby was kept NPO for 3 days, and enteral feedings with breast milk were started on day 4 and advanced as tolerated. The recovery was uneventful, and the baby was discharged home on day 5. He continues to do well on follow-up.

Conclusion

Even though its incidence has decreased significantly with formula modifications, lactobezoars (or milk curd syndrome) should be included in the differential diagnosis of newborns who develop acute intestinal obstruction.
新生儿乳黄(乳凝综合征)1例报告
乳黄或乳凝综合征(MCS)是新生儿小肠梗阻(SBO)的罕见病因。随着富含钙和脂肪配方奶粉的使用减少,其发病率有所下降,但仍有零星病例报告。病例介绍1例出生体重为3500g的足月新生儿,因呼吸窘迫、进食不耐受、进行性腹胀和多次胆汁性呕吐,于出生后第26天被送往急诊室。这名婴儿主要吃的是牛奶和断断续续的配方奶粉。在重症监护室进行初步复苏后,进行腹部x线检查,显示肠袢扩张,多个气液面,右侧髂窝出现磨砂样。他接受了腹部超声检查,排除了中肠扭转的可能。病人被送往手术室进行紧急剖腹手术。我们发现了明显的腹水,空肠正常,回肠和结肠严重扩张。回肠和结肠的管腔充满了凝乳状的内容物,或乳虫。肠壁也有肠性肺肿。通过温和的手动向前挤奶排出腔内内容物。不需要肠切除术。婴儿开始使用广谱抗生素,包括革兰氏阴性菌和厌氧菌。婴儿NPO喂养3天,第4天开始肠内喂养母乳,并逐渐耐受。康复过程很顺利,婴儿于第五天出院回家。他在随访中继续表现良好。结论虽然配方修改后乳糜泻(或乳凝综合征)的发生率明显降低,但仍应纳入新生儿急性肠梗阻的鉴别诊断。
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来源期刊
CiteScore
0.60
自引率
25.00%
发文量
348
审稿时长
15 days
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