Ethics of clinical research in Jordan: An overview

Q3 Medicine

Ethics, Medicine and Public Health Pub Date : 2025-01-01 DOI:10.1016/j.jemep.2025.101125

N.N. Abdelhadi

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引用次数: 0

Abstract

Background

Clinical research is crucial in advancing medical science and improving healthcare practices. In Jordan, international regulations have influenced the development of clinical research ethics, yet local challenges and areas for improvement still exist.

Objectives

The review aimed to map the ethical principles and frameworks applied in clinical research in Jordan and to provide recommendations for strengthening clinical research ethics in the country.

Methodology

A comprehensive search of PubMed, Medline, Clinical trials.gov, Google Scholar, Science Direct, ADI, and WHO databases was conducted through March 2025. Studies were selected based on relevance to ethical issues in clinical research, including participant consent, privacy, data protection, and research governance.

Results/discussion

Clinical research ethics in Jordan are guided by international frameworks, but several challenges hinder the effective implementation of these ethical principles. To ensure the highest standards of research conduct, researchers and ethical review committees need enhanced training.

Conclusion/perspectives

There are several opportunities for enhancing clinical research ethics in Jordan. Increasing the capacity and capability of IRBs through regular training and resource allocation can improve ethical oversight. Furthermore, promoting public awareness about clinical research ethics and the importance of informed consent can empower participants to make more informed decisions about their involvement in studies.

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约旦临床研究伦理：综述

临床研究对推进医学科学和改善医疗保健实践至关重要。在约旦，国际法规影响了临床研究伦理的发展，但当地的挑战和有待改进的领域仍然存在。目的该综述旨在绘制约旦临床研究中应用的伦理原则和框架，并为加强该国的临床研究伦理提供建议。方法到2025年3月，对PubMed、Medline、Clinical trials.gov、b谷歌Scholar、Science Direct、ADI和WHO数据库进行了全面检索。研究的选择基于临床研究中伦理问题的相关性，包括参与者同意、隐私、数据保护和研究治理。结果/讨论约旦的临床研究伦理是由国际框架指导的，但是一些挑战阻碍了这些伦理原则的有效实施。为了确保研究行为的最高标准，研究人员和伦理审查委员会需要加强培训。结论/观点约旦有几个加强临床研究伦理的机会。通过定期培训和资源分配来提高审计委员会的能力和能力，可以改善道德监督。此外，促进公众对临床研究伦理和知情同意的重要性的认识可以使参与者在参与研究时做出更明智的决定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ethics, Medicine and Public Health Medicine-Health Policy

CiteScore

2.20

自引率

0.00%

发文量

107

审稿时长

42 days

期刊介绍： This review aims to compare approaches to medical ethics and bioethics in two forms, Anglo-Saxon (Ethics, Medicine and Public Health) and French (Ethique, Médecine et Politiques Publiques). Thus, in their native languages, the authors will present research on the legitimacy of the practice and appreciation of the consequences of acts towards patients as compared to the limits acceptable by the community, as illustrated by the democratic debate.