Association between self-neglect and incident cognitive impairment among Chinese older adults and its subgroup differences

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2025-05-11 DOI:10.1016/j.archger.2025.105893

Yaqi Wang , Bowen Wan , Xueying Xu , Qingyun Lv , Yuan He , Jingwen Liu , Hairong Chang , Yue Zhao , Li Fu , Xiaoying Zang , Xiaonan Zhang

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引用次数: 0

Abstract

Background

Population aging has led to growing concerns regarding self-neglect and cognitive impairment among older adults. However, research on the association between self-neglect and incident cognitive impairment remains limited. We aimed to investigate the association between self-neglect and incident cognitive impairment and variations in gender and age.

Methods

A longitudinal study was conducted involving 2595 Chinese older adults from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database. Self-neglect was assessed using 17 items from the CLHLS, and cognitive function was evaluated using the Mini-Mental State Examination. Participants with cognitive impairment at baseline were excluded, and incident cognitive impairment during the follow-up period was documented. Cox proportional hazards models, restrictive cubic spline analysis (RCS), and stratified analyses based on gender and age (with 80 as the threshold) were conducted.

Results

The study sample comprised 1249 (48.1 %) men and 1346 (51.9 %) women, with an mean age of 79.7 ± 9.8 years. The risk of cognitive impairment was significantly higher for those in the third (Q3) and fourth (Q4) quartiles of self-neglect scores compared to those in the first quartile (Q1). The RCS analysis indicated a significantly linear relationship. The interaction between gender and self-neglect scores was significantly associated with incident cognitive impairment (P for interaction <0.001), suggesting that men are at a higher risk compared to women.

Conclusion

Self-neglect is identified as a significant risk factor for incident cognitive impairment among older adults, with a particular impact on men, highlighting the critical need to address self-neglect to prevent cognitive decline.

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中国老年人自我忽视与偶发性认知障碍的关系及其亚组差异

人口老龄化导致人们越来越关注老年人的自我忽视和认知障碍。然而，关于自我忽视与偶发性认知障碍之间关系的研究仍然有限。我们的目的是调查自我忽视与偶发性认知障碍之间的关系以及性别和年龄的差异。方法从中国健康长寿调查（CLHLS）数据库中选取2595名中国老年人进行纵向研究。使用CLHLS中的17个项目评估自我忽视，使用迷你精神状态检查评估认知功能。在基线时有认知障碍的参与者被排除在外，并记录了随访期间的认知障碍事件。进行了Cox比例风险模型、限制性三次样条分析（RCS）和基于性别和年龄（以80为阈值）的分层分析。结果男性1249例（48.1%），女性1346例（51.9%），平均年龄79.7±9.8岁。自我忽视得分第三（Q3）和第四（Q4）分位数的认知障碍风险明显高于第一（Q1）分位数的人。RCS分析显示两者有显著的线性关系。性别和自我忽视得分之间的相互作用与认知障碍事件显著相关（P为相互作用<；0.001），表明男性比女性有更高的风险。结论自我忽视被认为是老年人认知功能障碍的一个重要危险因素，对男性的影响尤甚，强调了解决自我忽视以预防认知能力下降的迫切需要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.