{"title":"ECG-derived DETERMINE score can provide information about procedure success in chronic total occlusion patients","authors":"Muzaffer Kahyaoğlu MD, Büşra Güvendi Şengör MD, Müge Ildızlı Demirbaş MD, Çetin Geçmen MD, Elnur Alizade MD, Regayip Zehir MD, Ali Karagöz MD","doi":"10.1016/j.jelectrocard.2025.154022","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Successful chronic total occlusion (CTO) interventions may provide symptomatic relief, improve left ventricular ejection fraction (LVEF), and improve clinical outcomes. In contrast, unsuccessful interventions may increase major adverse cardiovascular event rates. Several studies have investigated various scoring systems used to predict procedural success. The DETERMINE score is an electrocardiography (ECG) score that includes Q waves, fragmented QRS, and T wave inversions. This study aimed to investigate the relationship between the procedural success of CTO and the ECG-derived DETERMINE score system.</div></div><div><h3>Methods</h3><div>Our study included 301 patients. The patients were divided into successful revascularization (69 %) and unsuccessful revascularization (31 %).</div></div><div><h3>Results</h3><div>The unsuccessful revascularization group had a higher history of coronary artery disease, lower glomerular filtration rate (GFR) levels, lower left LVEF, higher j-CTO score, less good coronary collateral, higher retrograde approach, longer QRS interval, longer QT and QTc interval, and higher DETERMINE score than the successful revascularization group. The multivariate logistic regression test results indicated LVEF, j-CTO score, absence of good coronary collateral, and DETERMINE score as independent predictive parameters for unsuccessful revascularization.</div></div><div><h3>Conclusion</h3><div>Predicting procedural success in CTO patients is crucial, especially when selecting patients. The DETERMINE score, obtained from the ECG, may aid in decision-making.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"91 ","pages":"Article 154022"},"PeriodicalIF":1.3000,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of electrocardiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022073625001505","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Successful chronic total occlusion (CTO) interventions may provide symptomatic relief, improve left ventricular ejection fraction (LVEF), and improve clinical outcomes. In contrast, unsuccessful interventions may increase major adverse cardiovascular event rates. Several studies have investigated various scoring systems used to predict procedural success. The DETERMINE score is an electrocardiography (ECG) score that includes Q waves, fragmented QRS, and T wave inversions. This study aimed to investigate the relationship between the procedural success of CTO and the ECG-derived DETERMINE score system.
Methods
Our study included 301 patients. The patients were divided into successful revascularization (69 %) and unsuccessful revascularization (31 %).
Results
The unsuccessful revascularization group had a higher history of coronary artery disease, lower glomerular filtration rate (GFR) levels, lower left LVEF, higher j-CTO score, less good coronary collateral, higher retrograde approach, longer QRS interval, longer QT and QTc interval, and higher DETERMINE score than the successful revascularization group. The multivariate logistic regression test results indicated LVEF, j-CTO score, absence of good coronary collateral, and DETERMINE score as independent predictive parameters for unsuccessful revascularization.
Conclusion
Predicting procedural success in CTO patients is crucial, especially when selecting patients. The DETERMINE score, obtained from the ECG, may aid in decision-making.
期刊介绍:
The Journal of Electrocardiology is devoted exclusively to clinical and experimental studies of the electrical activities of the heart. It seeks to contribute significantly to the accuracy of diagnosis and prognosis and the effective treatment, prevention, or delay of heart disease. Editorial contents include electrocardiography, vectorcardiography, arrhythmias, membrane action potential, cardiac pacing, monitoring defibrillation, instrumentation, drug effects, and computer applications.