Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

Abstract

Popliteal artery adventitial disease (PAAD) underlies a significant portion of vascular conditions of the lower extremities, often culminating in critical limb ischemia and warranting a greater clinical understanding for effective management. Characterized by the cystic degeneration of the adventitia of the popliteal artery, PAAD remains a challenging condition both in terms of diagnosis and treatment. This review seeks to explore the complex pathophysiology, diagnostic criteria, and current management strategies, as well as discussing emerging therapies and future outlook for patients with PAAD.