IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report

Q4 Medicine

Radiology Case Reports Pub Date : 2025-05-15 DOI:10.1016/j.radcr.2025.04.028

Ning Xia , Wei Wang , Wei Zhang , Yan Li , Xiu-Hong Nie

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引用次数: 0

Abstract

We report a rare case of IgG4-related lung disease (RLD) with pulmonary lesions and recurrent pleural effusion to improve the diagnosis and treatment of this disease. A 60-year-old man was admitted to hospital for cough and dyspnea. CT scan showed a right lower lobe intrapulmonary mass with unilateral right-sided pleural effusion. Histology revealed no malignant findings. After 1 year, the patient re-admitted to our hospital with high serum level of IgG4 and IgE concentrations. CT scan demonstrated partial resolution of intrapulmonary mass and right-sided pleural effusion, while concurrently revealing interval development of substantial left-sided pleural effusion. The patient was diagnosed with IgG4-RLD by biopsy finally. This is a first case report of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly accumulating bilateral pleural effusions. Clinicians should consider the possibility of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly growing bilateral pleural effusion, particularly after rigorously excluding common diseases.

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igg4相关肺部疾病伴肺部病变及复发性胸腔积液1例

我们报告一例罕见的igg4相关肺部疾病（RLD）伴肺部病变和反复胸腔积液，以提高该病的诊断和治疗。一名60岁男子因咳嗽和呼吸困难入院。CT扫描显示右下肺内肿块伴单侧右侧胸腔积液。组织学未见恶性肿瘤。1年后，患者再次入院，血清IgG4和IgE浓度较高。CT扫描显示肺内肿块和右侧胸腔积液部分消退，同时显示左侧大量胸腔积液间歇发展。最终活检诊断为IgG4-RLD。这是首例IgG4-RLD肺内病变伴非同步、快速积累的双侧胸腔积液的病例报告。临床医生应考虑IgG4-RLD肺内病变伴非同步、快速增长的双侧胸腔积液的可能性，特别是在严格排除常见疾病后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.