Jin Yang, Dang-Wei Qian, Hong-Li Wang*, Gang-Wei Wang and Shang-Dong Yang*,
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引用次数: 0
Abstract
The biological importance and practical significance of H-phosphonate diesters and their analogues have been the major driving forces for research in various areas of synthetic organic phosphorus chemistry. However, establishment of a gentle and environmentally friendly method to avoid use of toxic PCl3 is still the biggest challenge in this area. As potential alternatives to PCl3, we studied the progress in the conversion of cheap and green inorganic salt sodium hypophosphite (NaH2PO2) and alcohol into various H-phosphonate diesters [(RO)2P(O)H] with the release of H2 by using the heterogeneous single-atom site Ni@CPOL-dppp&PPh3 catalyst. Remarkably, the catalyst exhibited outstanding catalytic performance, allowing for the efficient conversion of a wide range of various alcohols to their corresponding H-phosphonate diesters in good to high yields. This new route completely avoids the use of phosphorus trichloride (PCl3) and promises a convenient real process for making H-phosphonate diesters in industry and laboratory. Moreover, the present study provides meaningful insights into the development of well-defined heterogeneous catalysts guided by homogeneous catalysis.
期刊介绍:
ACS Catalysis is an esteemed journal that publishes original research in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. It offers broad coverage across diverse areas such as life sciences, organometallics and synthesis, photochemistry and electrochemistry, drug discovery and synthesis, materials science, environmental protection, polymer discovery and synthesis, and energy and fuels.
The scope of the journal is to showcase innovative work in various aspects of catalysis. This includes new reactions and novel synthetic approaches utilizing known catalysts, the discovery or modification of new catalysts, elucidation of catalytic mechanisms through cutting-edge investigations, practical enhancements of existing processes, as well as conceptual advances in the field. Contributions to ACS Catalysis can encompass both experimental and theoretical research focused on catalytic molecules, macromolecules, and materials that exhibit catalytic turnover.