A novel online vaping intervention and smoking prevention program for young adults who vape: protocol for a randomized controlled trial.

IF 3.7 2区医学 Q1 SUBSTANCE ABUSE

Addiction Science & Clinical Practice Pub Date : 2025-04-21 DOI:10.1186/s13722-025-00566-x

Denise D Tran, Jordan P Davis, Keegan Buch, Adam M Leventhal, Sarah W Feldstein Ewing, Eric R Pedersen

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引用次数: 0

Abstract

Background: E-cigarette use (i.e., vaping) is prevalent among young adults in the U.S. Studies show that young adults who vape are more likely to initiate cigarette smoking than young adults who do not vape. Despite this, little research on vaping interventions and prevention of smoking for young adults who vape exist.

Methods: A 2-arm pilot randomized controlled trial (RCT) will be conducted by recruiting young adults ages 18-24 who reported vaping at least once per week in the past 30 days and having never smoked cigarettes at baseline. Participants will be recruited via social media ads and be randomly assigned to an intervention arm, which will be the Live Free From E-cigarettes (LIFFE) mobile-based program (n = 50), or a waitlist control arm (n = 50). The primary outcomes are biochemically verified 7-day point prevalence abstinence for nicotine vaping, vaping reduction, and smoking susceptibility. Outcomes are measured at 2-, 4-, and 8-weeks after randomization.

Discussion: This is the first RCT to evaluate the effectiveness of a mobile-based intervention that targets smoking susceptibility while also supporting vaping cessation or vaping reduction in young adults. Findings may inform future efforts to prevent transition to cigarette smoking and vaping cessation and reduction in young adults.

Trial registration: ClinicalTrials.gov: NCT06129123; Date of registration: 11/10/2023.

查看原文本刊更多论文

一项针对吸电子烟的年轻人的新型在线电子烟干预和吸烟预防计划：一项随机对照试验方案。

背景：电子烟的使用（即电子烟）在美国年轻人中很普遍。研究表明，使用电子烟的年轻人比不使用电子烟的年轻人更有可能开始吸烟。尽管如此，对吸电子烟的年轻人进行干预和预防吸烟的研究很少。方法：一项两组随机对照试验（RCT）将招募年龄在18-24岁之间的年轻人进行，这些年轻人在过去30天内每周至少吸一次电子烟，并且在基线时从未吸烟。参与者将通过社交媒体广告招募，并被随机分配到干预组（n = 50），干预组将是基于移动的Live Free From E-cigarettes （LIFFE）项目（n = 50），或等候名单对照组（n = 50）。主要结果是经生化验证的7天尼古丁吸电子烟点流行戒烟、吸电子烟减少和吸烟易感性。在随机化后2周、4周和8周测量结果。讨论：这是第一项评估以移动设备为基础的干预措施有效性的随机对照试验，该干预措施针对吸烟易感性，同时也支持年轻人戒烟或减少吸烟。研究结果可能为未来防止年轻人过渡到吸烟和戒烟以及减少吸烟提供信息。试验注册：ClinicalTrials.gov: NCT06129123；注册日期：2023年10月11日。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Addiction Science & Clinical Practice Psychology-Clinical Psychology

CiteScore

3.90

自引率

10.80%

发文量

审稿时长

28 weeks

期刊介绍： Addiction Science & Clinical Practice provides a forum for clinically relevant research and perspectives that contribute to improving the quality of care for people with unhealthy alcohol, tobacco, or other drug use and addictive behaviours across a spectrum of clinical settings. Addiction Science & Clinical Practice accepts articles of clinical relevance related to the prevention and treatment of unhealthy alcohol, tobacco, and other drug use across the spectrum of clinical settings. Topics of interest address issues related to the following: the spectrum of unhealthy use of alcohol, tobacco, and other drugs among the range of affected persons (e.g., not limited by age, race/ethnicity, gender, or sexual orientation); the array of clinical prevention and treatment practices (from health messages, to identification and early intervention, to more extensive interventions including counseling and pharmacotherapy and other management strategies); and identification and management of medical, psychiatric, social, and other health consequences of substance use. Addiction Science & Clinical Practice is particularly interested in articles that address how to improve the quality of care for people with unhealthy substance use and related conditions as described in the (US) Institute of Medicine report, Improving the Quality of Healthcare for Mental Health and Substance Use Conditions (Washington, DC: National Academies Press, 2006). Such articles address the quality of care and of health services. Although the journal also welcomes submissions that address these conditions in addiction speciality-treatment settings, the journal is particularly interested in including articles that address unhealthy use outside these settings, including experience with novel models of care and outcomes, and outcomes of research-practice collaborations. Although Addiction Science & Clinical Practice is generally not an outlet for basic science research, we will accept basic science research manuscripts that have clearly described potential clinical relevance and are accessible to audiences outside a narrow laboratory research field.