Can the organic coating of breast tissue markers be sampled by an ultrasound-guided core cut biopsy without removing the clip marker? A proof-of-concept evaluation of two coated clip marker types in turkey breast tissue to improve representativity of ultrasound-guided core cut biopsies.

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Benedikt Schaefgen, Sabrina Steudt, Thomas Albrecht, Riku Togawa, Juliane Nees, Fabian Riedel, Michael Golatta, Jörg Heil
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引用次数: 0

Abstract

Purpose: The aim of this preclinical study was to test if the organic coating of two breast tissue clip markers (HydroMARK and UltraClip) can be sampled selectively by an ultrasound-guided core cut biopsy.

Methods: Ten clip markers of each type were inserted in four turkey breasts. Sonographic visibility was graded by the performing physicians. Core cut biopsy was performed, aiming to sample only the organic coating while leaving the clip marker in situ. Mammography, specimen radiography and gross inspection of the biopsy samples were conducted to evaluate dislocation or removal of the clips. The specimens were examined histopathologically to detect fragments of the coating material.

Results: HydroMARK was superior regarding biopsy feasibility and detectability of the coating. The organic coating of HydroMARK could be sampled selectively without dislocating the clip marker. Fragments of the coating material were visible macroscopically in 7 out of 10 biopsy specimens and could be detected in the histopathologic workup in 5 out of 10 specimens. The coating material of the UltraClip was not visible in any sample.

Conclusion: This study showed that the organic coating could be identified in core cut biopsy samples, both on a macroscopic and microscopic level. This could potentially be used to verify representativity of minimal invasive biopsies.

乳腺组织标记物的有机涂层能否通过超声引导的核心切片活检取样而不移除夹子标记物?火鸡乳房组织中两种涂覆夹标记物类型的概念验证评估,以提高超声引导核心切片活检的代表性。
目的:本临床前研究的目的是测试两种乳腺组织夹标记物(HydroMARK和UltraClip)的有机涂层是否可以通过超声引导的核心切片活检选择性取样。方法:在4只火鸡胸片中插入10个不同类型的夹子标记。超声显像的可见度由表演医师评定。进行岩心切片活检,目的是仅取样有机涂层,同时保留夹标记。对活检样本进行乳房x线摄影、标本x线摄影和大体检查,以评估夹的脱位或移除。对标本进行组织病理学检查,以检测涂层材料的碎片。结果:HydroMARK在活检的可行性和涂层的可检出性方面具有优越性。可以选择性地取样HydroMARK的有机涂层,而不会使夹标记物错位。10个活检标本中有7个在宏观上可见涂层材料碎片,10个标本中有5个在组织病理检查中可以检测到涂层材料碎片。UltraClip的涂层材料在任何样品中都不可见。结论:本研究表明,无论在宏观还是微观水平上,在岩心切片样本中都可以识别出有机涂层。这可能用于验证微创活检的代表性。
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来源期刊
Ultrasound
Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.70
自引率
0.00%
发文量
55
期刊介绍: Ultrasound is the official journal of the British Medical Ultrasound Society (BMUS), a multidisciplinary, charitable society comprising radiologists, obstetricians, sonographers, physicists and veterinarians amongst others.
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