{"title":"Recent advances in the study of the correlation between obstructive sleep apnea and thyroid-disorders.","authors":"Lu Zhai, Xiaoling Gao","doi":"10.1007/s11325-025-03350-y","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Epidemiological studies have revealed significant associations between obstructive sleep apnea (OSA) and thyroid disorders, but discrepancies and contradictory results remain in some studies. Given the limited research currently available on this topic, this article aims to review the relationship between OSA and thyroid diseases.</p><p><strong>Methods: </strong>PubMed, Embase, Web of Science, and The Cochrane Library were searched for the most recent literature on the correlation, mechanism, and treatment of OSA with various thyroid disorders for the last 10 years up to December 5, 2024.</p><p><strong>Results: </strong>There is a bidirectional association between OSA and thyroid disease. On the one hand, OSA not only increases the incidence of thyroid disorders, but also aggravates the severity of thyroid disorders, thereby negatively affecting treatment outcomes and prognosis; on the other hand, certain thyroid disorders may in turn promote the development of OSA.</p><p><strong>Conclusion: </strong>OSA is closely associated with the development of thyroid disease, but the specific mechanism is not clear. Effective treatments for thyroid disease combined with OSA need to be further investigated.</p>","PeriodicalId":21862,"journal":{"name":"Sleep and Breathing","volume":"29 2","pages":"176"},"PeriodicalIF":2.0000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sleep and Breathing","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11325-025-03350-y","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Epidemiological studies have revealed significant associations between obstructive sleep apnea (OSA) and thyroid disorders, but discrepancies and contradictory results remain in some studies. Given the limited research currently available on this topic, this article aims to review the relationship between OSA and thyroid diseases.
Methods: PubMed, Embase, Web of Science, and The Cochrane Library were searched for the most recent literature on the correlation, mechanism, and treatment of OSA with various thyroid disorders for the last 10 years up to December 5, 2024.
Results: There is a bidirectional association between OSA and thyroid disease. On the one hand, OSA not only increases the incidence of thyroid disorders, but also aggravates the severity of thyroid disorders, thereby negatively affecting treatment outcomes and prognosis; on the other hand, certain thyroid disorders may in turn promote the development of OSA.
Conclusion: OSA is closely associated with the development of thyroid disease, but the specific mechanism is not clear. Effective treatments for thyroid disease combined with OSA need to be further investigated.
目的:流行病学研究显示阻塞性睡眠呼吸暂停(OSA)与甲状腺疾病之间存在显著关联,但一些研究结果存在差异和矛盾。鉴于目前关于这一主题的研究有限,本文旨在综述OSA与甲状腺疾病的关系。方法:检索PubMed, Embase, Web of Science, The Cochrane Library,检索截至2024年12月5日的近10年关于OSA与各种甲状腺疾病的相关性、机制及治疗的最新文献。结果:OSA与甲状腺疾病存在双向相关性。一方面,OSA不仅增加了甲状腺疾病的发病率,而且加重了甲状腺疾病的严重程度,从而对治疗结果和预后产生负面影响;另一方面,某些甲状腺疾病可能反过来促进OSA的发展。结论:OSA与甲状腺疾病的发生发展密切相关,但具体机制尚不清楚。甲状腺疾病合并OSA的有效治疗方法有待进一步研究。
期刊介绍:
The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep.
Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.