Assessing the Effect of Automated Thermo-Mechanical Therapy on Abdominal Blood Flow With Magnetic Resonance Imaging.

IF 2.7 4区 医学 Q2 BIOPHYSICS
Jacek P Dmochowski, Luis Cardoso, Niranjan Khadka, Kiwon Lee, Sungjin Kim, Kaeun Kim, Hyelim Chun, Sunghye Choo, Hyun Jin Kim, Ahmed Duke Shereen, Marom Bikson
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Abstract

Thermal and mechanical tissue stimulation is widely utilized in various medical contexts, particularly to enhance local circulation, alleviate pain, and restore movement. Techniques to objectively quantify the physiological effects of these interventions support therapeutic efficacy and explain clinical benefits. Here we conducted a pilot trial to evaluate the feasibility of magnetic resonance imaging (MRI) technology to provide an objective assessment of acute treatment effects in enhancing blood flow. Subjects ( n = 10 $$ n=10 $$ ) received an MRI flow quantification scan of the abdominal aorta before and immediately after undergoing a 20-min thermo-mechanical massage delivered to the lumbar spine by a commercial automated device. We report a significant increase of 27% in the peak velocity of blood flow following treatment. There were no significant changes in the volume of the imaged vessel, in mean heart rate, or heart rate variability (HRV), which is consistent with direct local effects of therapy on circulation. These findings are consistent with the potential utility of MRI in detecting and quantifying regional increases in blood flow following thermo-mechanical stimulation.

磁共振成像评估自动热机械治疗对腹部血流的影响。
热和机械组织刺激广泛应用于各种医学环境,特别是促进局部循环,减轻疼痛和恢复运动。客观量化这些干预措施的生理效应的技术支持治疗效果并解释临床益处。在这里,我们进行了一项试点试验,以评估磁共振成像(MRI)技术的可行性,以提供一个客观的评估急性治疗效果,以促进血液流动。受试者(n = 10 $$ n=10 $$)在接受商用自动化设备对腰椎进行20分钟的热机械按摩之前和之后立即接受腹主动脉MRI流量量化扫描。我们报告说,人数显著增加了27人% in the peak velocity of blood flow following treatment. There were no significant changes in the volume of the imaged vessel, in mean heart rate, or heart rate variability (HRV), which is consistent with direct local effects of therapy on circulation. These findings are consistent with the potential utility of MRI in detecting and quantifying regional increases in blood flow following thermo-mechanical stimulation.
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来源期刊
NMR in Biomedicine
NMR in Biomedicine 医学-光谱学
CiteScore
6.00
自引率
10.30%
发文量
209
审稿时长
3-8 weeks
期刊介绍: NMR in Biomedicine is a journal devoted to the publication of original full-length papers, rapid communications and review articles describing the development of magnetic resonance spectroscopy or imaging methods or their use to investigate physiological, biochemical, biophysical or medical problems. Topics for submitted papers should be in one of the following general categories: (a) development of methods and instrumentation for MR of biological systems; (b) studies of normal or diseased organs, tissues or cells; (c) diagnosis or treatment of disease. Reports may cover work on patients or healthy human subjects, in vivo animal experiments, studies of isolated organs or cultured cells, analysis of tissue extracts, NMR theory, experimental techniques, or instrumentation.
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