Microalgae: A Treasure Trove of Anticancer Nutraceuticals and Promising Therapeutic Mechanisms.

IF 0.7 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Advanced biomedical research Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI:10.4103/abr.abr_101_24
Sajjad Masoumi, Maryam Zokaei, Ardavan Ahmadvand, Nogol Ghalamkarpour, Naghmeh Asadimanesh, Armin Azarimatin, Khashayar Fattah, Zahra Payandeh, Masoumeh Rostami, Afsaneh Farjami, Rajan Kumar Pandey, Mohsen Nabi-Afjadi
{"title":"Microalgae: A Treasure Trove of Anticancer Nutraceuticals and Promising Therapeutic Mechanisms.","authors":"Sajjad Masoumi, Maryam Zokaei, Ardavan Ahmadvand, Nogol Ghalamkarpour, Naghmeh Asadimanesh, Armin Azarimatin, Khashayar Fattah, Zahra Payandeh, Masoumeh Rostami, Afsaneh Farjami, Rajan Kumar Pandey, Mohsen Nabi-Afjadi","doi":"10.4103/abr.abr_101_24","DOIUrl":null,"url":null,"abstract":"<p><p>With cancer remaining a global health concern, the need for new and effective preventive and treatment methods is paramount. Microalgae have emerged as a potential source of anticancer nutraceuticals. Our research indicates that substances produced from microalgae, such as carotenoids, polyunsaturated fatty acids, phycocyanin, and polysaccharides, have shown anticancer effects in both laboratory and human investigations. Carotenoids, including astaxanthin, have shown the ability to hinder the development of tumors and trigger programmed cell death (apoptosis) in several types of cancer cells. Moreover, studies have shown that phycocyanin, a blue pigment present in some species of microalgae, has properties that help reduce inflammation and combat cancer. Potential future research directions include expanding the scope of the study to encompass a diverse range of microalgae species, identifying other compounds with anticancer properties, and investigating the mechanisms by which chemicals derived from microalgae function in the treatment and prevention of cancer. Moreover, it is important to establish scalable and sustainable procedures for the industrial production of compounds derived from microalgae. In conclusion, our evaluation reveals that microalgae have enormous potential as a source of anticancer nutraceuticals, containing a variety of bioactive substances that could eventually lead to the development of novel and effective cancer prevention and treatment methods. To realize the maximum potential of chemicals derived from microalgae, it is necessary to develop a sustainable and environmentally benign industry and to continue research in this area.</p>","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"14 ","pages":"5"},"PeriodicalIF":0.7000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981035/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced biomedical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/abr.abr_101_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

Abstract

With cancer remaining a global health concern, the need for new and effective preventive and treatment methods is paramount. Microalgae have emerged as a potential source of anticancer nutraceuticals. Our research indicates that substances produced from microalgae, such as carotenoids, polyunsaturated fatty acids, phycocyanin, and polysaccharides, have shown anticancer effects in both laboratory and human investigations. Carotenoids, including astaxanthin, have shown the ability to hinder the development of tumors and trigger programmed cell death (apoptosis) in several types of cancer cells. Moreover, studies have shown that phycocyanin, a blue pigment present in some species of microalgae, has properties that help reduce inflammation and combat cancer. Potential future research directions include expanding the scope of the study to encompass a diverse range of microalgae species, identifying other compounds with anticancer properties, and investigating the mechanisms by which chemicals derived from microalgae function in the treatment and prevention of cancer. Moreover, it is important to establish scalable and sustainable procedures for the industrial production of compounds derived from microalgae. In conclusion, our evaluation reveals that microalgae have enormous potential as a source of anticancer nutraceuticals, containing a variety of bioactive substances that could eventually lead to the development of novel and effective cancer prevention and treatment methods. To realize the maximum potential of chemicals derived from microalgae, it is necessary to develop a sustainable and environmentally benign industry and to continue research in this area.

微藻:抗癌营养品的宝库和有前景的治疗机制。
由于癌症仍然是一个全球性的健康问题,对新的和有效的预防和治疗方法的需求至关重要。微藻已成为抗癌营养品的潜在来源。我们的研究表明,从微藻中产生的物质,如类胡萝卜素、多不饱和脂肪酸、藻蓝蛋白和多糖,在实验室和人体研究中都显示出抗癌作用。类胡萝卜素,包括虾青素,在几种类型的癌细胞中显示出阻碍肿瘤发展和触发程序性细胞死亡(凋亡)的能力。此外,研究表明,藻蓝蛋白,一种存在于某些微藻物种中的蓝色色素,具有有助于减少炎症和对抗癌症的特性。潜在的未来研究方向包括扩大研究范围以涵盖各种微藻物种,识别具有抗癌特性的其他化合物,以及研究从微藻中提取的化学物质在治疗和预防癌症中的作用机制。此外,建立可扩展和可持续的微藻化合物工业生产程序也很重要。总之,我们的评价表明,微藻作为抗癌营养保健品的来源具有巨大的潜力,它含有多种生物活性物质,最终可能导致开发新的有效的癌症预防和治疗方法。为了最大限度地发挥微藻衍生化学品的潜力,必须发展一个可持续的、环境友好的产业,并继续在这一领域进行研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
0.90
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信