The Effect of Web-Based Education on Symptoms and Adherence To Immunosuppressive Medications In Liver Transplant Patients

IF 0.8 4区医学 Q4 IMMUNOLOGY

Transplantation proceedings Pub Date : 2025-04-29 DOI:10.1016/j.transproceed.2025.03.005

Nihal Dolanbay , Meral Ozkan

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引用次数: 0

Abstract

Aim

Liver transplant patients experience several symptoms associated with immunosuppressive medications and have problems in medication adherence. This study aims to examine the effect of web-based education on symptoms and adherence to immunosuppressive medications in liver transplant patients.

Materials and Methods

This is a randomized controlled trial study. The population of the study consisted of patients who had liver transplantation in a university hospital at least 2 months and at most 2 years before the interview (N = 116). The sample of the study consisted of a total of 90 liver transplant patients who were determined by a power analysis. The data were collected between January and July 2021 using a patient information form, the Modified Transplant Symptom Occurrence and Symptom Distress Scale-59 Items (MTSOSD-59), and the Immunosuppressive Medication Adherence Scale (IMAS).

Results

Liver transplant patients in the experimental group were given a web-based education for 1 month. After the education, a significant decrease was observed in their symptom’s occurrence and discomfort with symptoms scores and a significant increase in their immunosuppressive medication adherence scores, compared to that of those in the control group (P < .05).

Conclusion

As a result, the web-based education reduced the symptoms and discomfort associated with immunosuppressive medications in liver transplant patients and increased their immunosuppressive medication adherence.

查看原文本刊更多论文

网络教育对肝移植患者症状及免疫抑制药物依从性的影响。

目的：肝移植患者经历与免疫抑制药物相关的几种症状，并且在药物依从性方面存在问题。本研究旨在探讨网络教育对肝移植患者症状和免疫抑制药物依从性的影响。材料与方法：本研究为随机对照试验研究。该研究的人群包括在访谈前至少2个月至最多2年在大学医院接受肝移植的患者（N = 116）。该研究的样本由90名肝移植患者组成，他们是通过功率分析确定的。数据收集于2021年1月至7月，使用患者信息表，改良移植症状发生和症状困扰量表-59项（MTSOSD-59）和免疫抑制药物依从性量表（IMAS）。结果：试验组肝移植患者接受为期1个月的网络教育。教育后患者症状发生及不适症状评分明显低于对照组，免疫抑制药物依从性评分明显高于对照组（P < 0.05）。结论：基于网络的教育减少了肝移植患者与免疫抑制药物相关的症状和不适，并增加了他们对免疫抑制药物的依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transplantation proceedings 医学-免疫学

CiteScore

1.70

自引率

0.00%

发文量

502

审稿时长

60 days

期刊介绍： Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.