A comprehensive evaluation of intramedullary devices in the management of femoral metastasis: 30-day outcomes.

Q3 Medicine
Baylor University Medical Center Proceedings Pub Date : 2025-02-28 eCollection Date: 2025-01-01 DOI:10.1080/08998280.2025.2465058
Halil Bulut, Maria Jose Maestre, Daniel Tomey
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Abstract

Introduction: Bone metastases, affecting 40% to 60% of patients with metastatic disease, are a significant concern, with the femur being one of the most common sites. These metastases significantly impact quality of life and present complex treatment challenges. Intramedullary nailing (IMN) is frequently used for femoral metastases owing to its minimally invasive nature and favorable outcomes.

Methods: A retrospective cohort analysis was performed using data from the American College of Surgeons National Surgical Quality Improvement Program database (2016-2021). Patients aged 18 and older who underwent IMN for metastatic femoral disease were included. The primary endpoints were 30-day reoperation and readmission rates. Secondary endpoints assessed 30-day postoperative complications.

Results: The cohort primarily comprised female patients (62.7%, n = 482) with notable comorbidities such as hypertension (48.9%) and high smoking rates (71.3%). Low rates of specific reoperations (0.4%, n = 3) and unplanned reoperations (1.7%, n = 13) were observed within 30 days. The incidence of deep vein thrombosis was 1.2%, and the incidence of pulmonary embolism was 0.7%. Surgical site infections were rare (Figure 1).

Conclusion: IMN is a safe and effective surgical option for treating metastatic femoral lesions, providing a favorable safety profile. Further research is recommended to explore thromboembolic risks and optimize preventive strategies.

综合评价髓内装置在股骨转移治疗中的作用:30天的结果。
导读:骨转移,影响40%至60%的转移性疾病患者,是一个重要的问题,股骨是最常见的部位之一。这些转移显著影响生活质量,并带来复杂的治疗挑战。髓内钉(IMN)因其微创性和良好的预后而经常用于股骨转移。方法:采用美国外科医师学会国家手术质量改进计划数据库(2016-2021)的数据进行回顾性队列分析。18岁及以上因转移性股骨疾病接受IMN治疗的患者被纳入研究。主要终点为30天再手术率和再入院率。次要终点评估术后30天并发症。结果:该队列主要由女性患者组成(62.7%,n = 482),并伴有高血压(48.9%)和高吸烟率(71.3%)等显著合并症。30 d内特殊再手术率低(0.4%,n = 3),计划外再手术率低(1.7%,n = 13)。深静脉血栓的发生率为1.2%,肺栓塞的发生率为0.7%。手术部位感染罕见(图1)。结论:IMN是一种安全有效的治疗转移性股骨病变的手术选择,具有良好的安全性。建议进一步研究血栓栓塞风险并优化预防策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
245
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