{"title":"Long-Term Trends in the Burden of Migraine in China: A Comprehensive Analysis from 1990 to 2021 and Projections to 2035.","authors":"Cifeng Zhang, Xiaoping Wang","doi":"10.1159/000545886","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Migraine is a widespread neurological disorder that significantly affects quality of life. However, data on its burden in China remain limited. This study analyzes long-term trends (1990-2021) and projects future patterns.</p><p><strong>Methods: </strong>Using the Global Burden of Disease (GBD) 2021 database, we examined migraine incidence, prevalence, and disability-adjusted life-years (DALYs). Temporal trends were assessed via joinpoint regression, while age-period-cohort (APC) analysis and decomposition analyses identified key influences. Bayesian APC modeling projected future trends through 2035.</p><p><strong>Results: </strong>Migraine imposes a substantial health burden in China, with an annual incidence of 13.04 million cases, a prevalence of 184.75 million cases, and 6.98 million DALYs cases. Females are disproportionately affected, with peak prevalence occurs in the 30-49 age group. Individuals born post-1960 show increased susceptibility, as linked to demographic and lifestyle shifts. Population growth is a major driver of rising prevalence, with projections indicating a continued increase through 2035.</p><p><strong>Conclusion: </strong>Migraine remains a significant public health concern in China, particularly among women. Targeted prevention, early detection, and intervention strategies are essential to mitigate its growing burden.</p>","PeriodicalId":54730,"journal":{"name":"Neuroepidemiology","volume":" ","pages":"1-13"},"PeriodicalIF":4.0000,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroepidemiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000545886","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Migraine is a widespread neurological disorder that significantly affects quality of life. However, data on its burden in China remain limited. This study analyzes long-term trends (1990-2021) and projects future patterns.
Methods: Using the Global Burden of Disease (GBD) 2021 database, we examined migraine incidence, prevalence, and disability-adjusted life-years (DALYs). Temporal trends were assessed via joinpoint regression, while age-period-cohort (APC) analysis and decomposition analyses identified key influences. Bayesian APC modeling projected future trends through 2035.
Results: Migraine imposes a substantial health burden in China, with an annual incidence of 13.04 million cases, a prevalence of 184.75 million cases, and 6.98 million DALYs cases. Females are disproportionately affected, with peak prevalence occurs in the 30-49 age group. Individuals born post-1960 show increased susceptibility, as linked to demographic and lifestyle shifts. Population growth is a major driver of rising prevalence, with projections indicating a continued increase through 2035.
Conclusion: Migraine remains a significant public health concern in China, particularly among women. Targeted prevention, early detection, and intervention strategies are essential to mitigate its growing burden.
期刊介绍:
''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.