Hyung-Kyum Kim, Byung-Kun Kim, Jung-Ju Lee, Kyusik Kang, Woong-Woo Lee, Ilhan Yoo, Namoh Kim
{"title":"Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report.","authors":"Hyung-Kyum Kim, Byung-Kun Kim, Jung-Ju Lee, Kyusik Kang, Woong-Woo Lee, Ilhan Yoo, Namoh Kim","doi":"10.47936/encephalitis.2025.00010","DOIUrl":null,"url":null,"abstract":"<p><p>Tuberculous meningitis (TBM) is fatal unless treated promptly. Nonconvulsive status epilepticus (NCSE) may cause altered consciousness in patients with TBM. A 25-year-old female presented to the emergency department with a headache and fever along with multiple associated symptoms that had developed 2 days prior. Based on clinical findings, brain imaging, and cerebrospinal fluid (CSF) examination, she was tentatively diagnosed with viral meningitis. Later, she developed altered consciousness with focal seizures, and follow-up CSF examination findings and electroencephalography were consistent with NCSE complicated by TBM. We encountered a patient with TBM who exhibited initial atypical CSF findings and NCSE, and we report the case here and discuss the pathomechanisms.</p>","PeriodicalId":72904,"journal":{"name":"Encephalitis (Seoul, Korea)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Encephalitis (Seoul, Korea)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47936/encephalitis.2025.00010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Tuberculous meningitis (TBM) is fatal unless treated promptly. Nonconvulsive status epilepticus (NCSE) may cause altered consciousness in patients with TBM. A 25-year-old female presented to the emergency department with a headache and fever along with multiple associated symptoms that had developed 2 days prior. Based on clinical findings, brain imaging, and cerebrospinal fluid (CSF) examination, she was tentatively diagnosed with viral meningitis. Later, she developed altered consciousness with focal seizures, and follow-up CSF examination findings and electroencephalography were consistent with NCSE complicated by TBM. We encountered a patient with TBM who exhibited initial atypical CSF findings and NCSE, and we report the case here and discuss the pathomechanisms.