Cai Hu, Huahui Liu, Yi Zhang, Shuxian Xu, Shuang Liang, Jing Yang, Qiqi Liu, Erjiao Xu
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引用次数: 0
Abstract
Objective: This study aimed to analyze the risk factors that cause hoarseness after microwave ablation (MWA) and establish a visual zoning approach combined with a nomogram to predict the risk of hoarseness after MWA.
Methods: Retrospective analysis of the images and clinical data of patients with thyroid nodules who underwent MWA was carried out from January 2021 to September 2024. Patients were divided into benign thyroid nodule and papillary thyroid cancer (PTC) groups. Parameters related to hoarseness were analyzed, including age, sex, multifocality, glandular thickness, nodule components, ablation power, nodule location, maximum nodule diameter and nodule distance from the thyroid capsule and tracheoesophageal groove, as well as a new "three-zone method." Three different prediction models and a nomogram were constructed to predict the risk of hoarseness.
Results: A total of 446 patients (126 males and 320 females; median age 44 years) with a total of 542 nodules were included in this study. The overall incidence rate of hoarseness after MWA was 2.9% (13/446), while it was 2.2% (5/223) in the benign nodule group and 3.6% (8/223) in the PTC group. Multivariate analysis showed that away from anterior capsule distance, close to tracheoesophageal groove distance and location in zone 3 were risk factors of hoarseness after MWA for PTC nodules. The above variables and outcomes were visualized via nomogram (C-index = 0.910).
Conclusion: This combined model with the "three-zone method" and established nomogram could be employed to predict the incidence of hoarseness after MWA for PTC.
期刊介绍：
Ultrasound in Medicine and Biology is the official journal of the World Federation for Ultrasound in Medicine and Biology. The journal publishes original contributions that demonstrate a novel application of an existing ultrasound technology in clinical diagnostic, interventional and therapeutic applications, new and improved clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and the interactions between ultrasound and biological systems, including bioeffects. Papers that simply utilize standard diagnostic ultrasound as a measuring tool will be considered out of scope. Extended critical reviews of subjects of contemporary interest in the field are also published, in addition to occasional editorial articles, clinical and technical notes, book reviews, letters to the editor and a calendar of forthcoming meetings. It is the aim of the journal fully to meet the information and publication requirements of the clinicians, scientists, engineers and other professionals who constitute the biomedical ultrasonic community.
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