Sleep Quality and Its Influencing Factors in Hemodialysis and Renal Transplant Patients Across Various Stages

IF 0.8 4区医学 Q4 IMMUNOLOGY

Transplantation proceedings Pub Date : 2025-05-01 DOI:10.1016/j.transproceed.2025.03.002

Xu Zhang , Xu-Liang Yang , Yao-Hong Liu , Xin-Ping Lei , Xu-Feng Zhang , Qiu-Xiang Kang

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引用次数: 0

Abstract

Objective

Sleep disorder is a prominent clinical symptom in CKD patients. It is highly prevalent and harmful and is related to numerous influencing factors. The aim of this study was to analyze the possible influencing factors of hemodialysis and renal transplant patients at different periods.

Methods

Twenty-six patients were selected in each of the following groups: hemodialysis (group A), 3 months after renal transplantation (group B), 3 to 12 months after renal transplantation (group C), and more than 1 year after renal transplantation (group D).The patients' sleep quality was evaluated by the Pittsburgh Sleep Quality Index (PSQI). This study collected clinical and laboratory data related to sleep problems, such as creatinine, calcium, phosphorus, potassium, hemoglobin, albumin and alkaline phosphatase, while also investigating psychological conditions such as depression and anxiety. Multiple linear regression was used to predict sleep status based on anxiety, depression, creatinine, blood calcium, blood phosphorus, blood potassium, hemoglobin and albumin.

Results

Compared with group A, the scores of PSQI in groups B and C were significantly lower, and the differences were statistically significant (P ≤ .05); however the differences were not significant in group D (P ≥ .05).Among the eight independent variables, anxiety, creatinine, and blood phosphorus significantly influenced sleep status (P ≤ .05). Conversely, depression, blood calcium, blood potassium, hemoglobin, and albumin did not show a statistically significant effect on sleep status (P ≥ .05).

Conclusion

After renal transplantation, patients' sleep status deteriorated after one year after surgery. Our study revealed that anxiety, creatinine and blood phosphorus were risk factors affecting sleep, which deserves our focused attention.

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血液透析和肾移植患者各阶段睡眠质量及其影响因素

目的：睡眠障碍是CKD患者的一个突出临床症状。它是高度流行和有害的，与许多影响因素有关。本研究的目的是分析血液透析和肾移植患者在不同时期可能的影响因素。方法：选择血液透析组（A组）、肾移植术后3个月组（B组）、肾移植术后3 ~ 12个月组（C组）、肾移植术后1年以上组（D组），每组26例。采用匹兹堡睡眠质量指数（PSQI）评价患者的睡眠质量。这项研究收集了与睡眠问题相关的临床和实验室数据，如肌酐、钙、磷、钾、血红蛋白、白蛋白和碱性磷酸酶，同时也调查了心理状况，如抑郁和焦虑。以焦虑、抑郁、肌酐、血钙、血磷、血钾、血红蛋白、白蛋白为指标，采用多元线性回归预测睡眠状态。结果：与A组比较，B、C组患者PSQI评分均显著降低，差异均有统计学意义（P≤0.05）；D组差异无统计学意义（P≥0.05）。8个自变量中，焦虑、肌酐、血磷显著影响睡眠状态（P≤0.05）。相反，抑郁、血钙、血钾、血红蛋白和白蛋白对睡眠状态的影响无统计学意义（P≥0.05）。结论：肾移植术后患者睡眠状态在术后1年出现恶化。我们的研究表明，焦虑、肌酐和血磷是影响睡眠的危险因素，值得我们关注。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transplantation proceedings 医学-免疫学

CiteScore

1.70

自引率

0.00%

发文量

502

审稿时长

60 days

期刊介绍： Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.