Comparison of Laparoscopic Single-Anastomosis Duodenal-Jejunal Bypass With Sleeve Gastrectomy and Laparoscopic Roux-en-Y Gastric Bypass on Short-term Outcomes in Patients With Obesity.

Abstract

Purpose: The aim of this study was to compare postoperative course of laparoscopic single-anastomosis duodenal-jejunal bypass with sleeve gastrectomy (SADJB-SG) and laparoscopic Roux-en-Y gastric bypass (RYGB) during a 1-year follow-up period.

Materials and methods: Electronic medical records of all patients who underwent SADJB-SG and RYGB between March 2019 and June 2021 at a single institution were retrospectively reviewed. Surgical outcomes, weight loss, resolution of co-morbidities, episode of dumping syndrome, and marginal ulcer at endoscopy were assessed.

Results: Eighty-four patients who underwent SADJB-SG and RYGB were enrolled. One-year follow-up rate was 78.6%. There were no significant differences in operative time, estimated blood loss, length of postoperative stay, postoperative complications, readmission, or reoperation rate between SADJB-SG and RYGB. Percent of total weight loss (%TWL) was 26.9±9.3% in SADJB-SG and 29.6±7.6% in RYGB (P=0.209). Remission rates of T2DM, hypertension, dyslipidemia, and GERD were 78.3%, 63.6%, 44.4%, and 40% in SADJB-SG and 71.4%, 52.9%, 56.2%, and 12.5% in RYGB (P=0.318, P=0.480, P=0.417, and P=0.561), respectively. Episodes of dumping syndrome and marginal ulcer at endoscopy showed rates of 0% and 0% in SADJB-SG and 33.4% and 15.8% in RYGB (P=0.002 and P=0.043), respectively.

Conclusion: SADJB-SG is comparable to RYGB in terms of perioperative outcomes, weight loss, and resolution of co-morbidities. It is advantageous in terms of dumping syndrome and marginal ulcer during 1-year follow-up.