Enteral Nutrition in Newborns with Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Medical Bulletin of Sisli Etfal Hospital Pub Date : 2025-03-18 eCollection Date: 2025-01-01 DOI:10.14744/SEMB.2025.34356
Mehmet Fatih Deveci, Zehra Arslan, Ayse Unal Yuksekgonul, Osman Kosek
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引用次数: 0

Abstract

Objectives: Clinicians are uncertain about the nutrition of patients diagnosed with hypoxic-ischemic encephalopathy due to the risk of necrotizing enterocolitis and feeding intolerance. The nutritional protocols of these patients are still unclear. We aimed to investigate the time of starting nutrition and related conditions in these patients receiving therapeutic hypothermia (TH) treatment.

Methods: This retrospective single-center study evaluated patients hospitalized at our unit and receiving TH between January 2022 and June 2023. Those who started nutrition during TH and after TH were defined as the early enteral nutrition (EEN) and late enteral nutrition (LEN) groups, respectively. Analyses were performed between the two groups.

Results: Our study evaluated 91 patients, of whom 40 were in the EEN group and 51 were in the LEN group. The reaching birth weight time in the LEN group was delayed (10 [5-22] vs. 7.5 [5-25] days, respectively, p<0.001), the transition time to full enteral nutrition was longer (10 [6-20] vs. 7 [5-18] days, respectively, p<0.001), and the hospitalization time was longer (13 [8-43] vs. 9 [7-35] days, respectively, p<0.001) compared with those of the EEN group.

Conclusion: TH is not an obstacle to starting nutrition. Starting nutrition in these patients at an early stage does not increase nutritional complications and shortens their discharge time.

治疗性低温下新生儿缺氧缺血性脑病的肠内营养。
目的:由于坏死性小肠结肠炎和喂养不耐受的风险,临床医生对诊断为缺氧缺血性脑病的患者的营养不确定。这些患者的营养方案尚不清楚。我们的目的是调查这些接受治疗性低温治疗的患者开始营养的时间和相关情况。方法:这项回顾性单中心研究评估了2022年1月至2023年6月期间在我单位住院并接受TH治疗的患者。在TH期间和TH之后开始营养的患者分别被定义为早期肠内营养(EEN)组和晚期肠内营养(LEN)组。对两组患者进行分析。结果:我们的研究评估了91例患者,其中40例为EEN组,51例为LEN组。LEN组达到出生体重的时间分别延迟了10[5-22]天和7.5[5-25]天。结论:TH不是开始营养的障碍。这些患者在早期开始营养不会增加营养并发症并缩短出院时间。
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来源期刊
Medical Bulletin of Sisli Etfal Hospital
Medical Bulletin of Sisli Etfal Hospital MEDICINE, GENERAL & INTERNAL-
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16.70%
发文量
41
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