{"title":"Harnessing medicinal maggot excretions/secretions for the ocular surface: A mini review.","authors":"Ebenezer Owusu, Rachel L Redfern","doi":"10.1016/j.clae.2025.102422","DOIUrl":null,"url":null,"abstract":"<p><p>Ophthalmology could significantly benefit from the therapeutic potential of medicinal maggots, which have been extensively utilized in dermatology for wound healing and infection management. This article reviews the evidence supporting the potential translation of maggot excretions/secretions (ES) for treating ocular surface wounds and infections. It examines the challenges associated with treating ocular surface wounds and infections, the established role of medicinal maggots in chronic skin wound care, and the composition and biological properties of maggot ES. Furthermore, recent research on the impact of maggot ES on the ocular surface is highlighted, along with future research directions necessary to effectively harness its bioactive components for ocular surface-related treatments.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102422"},"PeriodicalIF":4.1000,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contact Lens & Anterior Eye","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clae.2025.102422","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Ophthalmology could significantly benefit from the therapeutic potential of medicinal maggots, which have been extensively utilized in dermatology for wound healing and infection management. This article reviews the evidence supporting the potential translation of maggot excretions/secretions (ES) for treating ocular surface wounds and infections. It examines the challenges associated with treating ocular surface wounds and infections, the established role of medicinal maggots in chronic skin wound care, and the composition and biological properties of maggot ES. Furthermore, recent research on the impact of maggot ES on the ocular surface is highlighted, along with future research directions necessary to effectively harness its bioactive components for ocular surface-related treatments.
期刊介绍：
Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.
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