Estimating endurance training intensity prescription from the 6-minute stepper test in people with chronic obstructive pulmonary disease - a multicenter cross-sectional study with external validation.

IF 10.4 2区 医学 Q1 RESPIRATORY SYSTEM
Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-04-11 DOI:10.1080/25310429.2025.2486875
Tristan Bonnevie, Augustin Clet, Marc Beaumont, Pauline Smondack, Yann Combret, Clément Médrinal, Guillaume Prieur, Fairuz Boujibar, Jean-François Muir, Antoine Cuvelier, Jean-Marie Grosbois, David Debeaumont, Elise Artaud-Macari, Francis-Edouard Gravier
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引用次数: 0

Abstract

Background: Home-based pulmonary rehabilitation (PR) can enhance accessibility to PR, but no at-home field exercise test has been validated for individualized endurance training prescriptions.

Research question: What is the accuracy of the six-minute stepper test (6MST) in estimating endurance training intensity as determined during cardiopulmonary exercise testing (CPET)?

Study design and method: This multicenter (N = 3) cross-sectional study included individuals with COPD. Participants performed CPET and two 6MSTs to evaluate the 6MST's ability to estimate endurance training intensity based on CPET-derived heart rate at the first ventilatory threshold (HRvt1), the corresponding power output (Pvt1), and peak power output (Ppeak). Predictive equations were tested for external validity using data from two prior studies.

Results: 105 patients were included (mean age 61 (SD 9) years; mean FEV1 61 (SD 21) %). Predictive equations moderately predicted HRvt1 (r² = 0.38), strongly predicted Pvt1 (r² = 0.63) and very strongly predicted Ppeak (r² = 0.75). External validity was small to moderate for HRvt1 and Pvt1 but was strong for 60% of Ppeak (mean absolute difference: 10W, 95% CI 5 to 10). Passing and Bablok regression confirmed interchangeability for Pvt1 and 60% of Ppeak.

Interpretation: The 6MST offers a reliable method to set initial training intensity when CPET is unavailable.

Clinical trial registration: NCT02842463.

从慢性阻塞性肺疾病患者的6分钟步进试验中估计耐力训练强度处方——一项具有外部验证的多中心横断面研究
背景:以家庭为基础的肺康复(PR)可以提高对PR的可及性,但没有家庭野外运动试验被验证为个体化耐力训练处方。研究问题:在心肺运动测试(CPET)中确定的6分钟步进测试(6MST)在估计耐力训练强度方面的准确性是多少?研究设计和方法:这项多中心(N = 3)横断面研究纳入了COPD患者。参与者进行CPET和两次6MST,以评估6MST基于CPET衍生的第一次通气阈值心率(HRvt1),相应的功率输出(Pvt1)和峰值功率输出(Ppeak)估计耐力训练强度的能力。使用先前两项研究的数据对预测方程进行外部有效性检验。结果:纳入105例患者,平均年龄61岁(SD 9);平均FEV1 61 (SD 21) %)。预测方程适度预测HRvt1 (r²= 0.38),强烈预测Pvt1 (r²= 0.63),非常强烈预测Ppeak (r²= 0.75)。HRvt1和Pvt1的外部效度为小到中等,但Ppeak的60%的外部效度很强(平均绝对差:10W, 95% CI 5至10)。通过和Bablok回归证实了Pvt1和Ppeak 60%的互换性。解释:当没有CPET时,6MST提供了一种可靠的方法来设定初始训练强度。临床试验注册:NCT02842463。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pulmonology
Pulmonology Medicine-Pulmonary and Respiratory Medicine
CiteScore
14.30
自引率
5.10%
发文量
159
审稿时长
19 days
期刊介绍: Pulmonology (previously Revista Portuguesa de Pneumologia) is the official journal of the Portuguese Society of Pulmonology (Sociedade Portuguesa de Pneumologia/SPP). The journal publishes 6 issues per year and focuses on respiratory system diseases in adults and clinical research. It accepts various types of articles including peer-reviewed original articles, review articles, editorials, and opinion articles. The journal is published in English and is freely accessible through its website, as well as Medline and other databases. It is indexed in Science Citation Index Expanded, Journal of Citation Reports, Index Medicus/MEDLINE, Scopus, and EMBASE/Excerpta Medica.
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