Update in management of microbial keratitis associated with contact lenses.

IF 3 2区医学 Q1 OPHTHALMOLOGY

Current Opinion in Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-04-10 DOI:10.1097/ICU.0000000000001143

Christine Xu, Bohan Xing, Jennifer Y Li

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引用次数: 0

Abstract

Purpose of review: The rising prevalence of contact lens wear is associated with increased contact lens-related complications, with one of the most serious being contact lens (CL)-associated microbial keratitis (MK). We describe updated prevention and management strategies of this sight-threatening condition.

Recent findings: Poor contact lens hygiene and practices remain the most common predisposing factors for CL-associated MK. Management currently relies largely on antimicrobial therapy guided by culture data; however, increasing antimicrobial resistance is a worldwide concern. Recent studies show early promise for novel broad-spectrum therapies including cross-linking and rose Bengal-photodynamic therapy, povidone iodine, and antimicrobial peptides.

Summary: There has been increased investigation in past years into broad-spectrum nonselective treatments for MK. While these investigations show early promise, prevention of CL-associated MK through education on hygiene practices remains an important healthcare intervention.

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与隐形眼镜相关的微生物角膜炎管理的最新进展。

综述目的：隐形眼镜佩戴率的上升与隐形眼镜相关并发症的增加有关，其中最严重的是隐形眼镜（CL）相关的微生物角膜炎（MK）。我们描述了最新的预防和管理策略，这种视力威胁的条件。最新发现：不良的隐形眼镜卫生和使用习惯仍然是cl相关MK最常见的诱发因素。目前的治疗主要依赖于由培养数据指导的抗菌治疗；然而，抗菌素耐药性的增加是一个全球关注的问题。最近的研究显示了新型广谱疗法的早期前景，包括交联和玫瑰光动力疗法、聚维酮碘和抗菌肽。摘要：在过去的几年中，对广谱非选择性治疗MK的研究有所增加。虽然这些研究显示出早期的希望，但通过卫生习惯教育预防cl相关的MK仍然是一项重要的医疗干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Ophthalmology 医学-眼科学

CiteScore

6.80

自引率

5.40%

发文量

120

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Ophthalmology is an indispensable resource featuring key up-to-date and important advances in the field from around the world. With renowned guest editors for each section, every bimonthly issue of Current Opinion in Ophthalmology delivers a fresh insight into topics such as glaucoma, refractive surgery and corneal and external disorders. With ten sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, clinicians and other healthcare professionals alike.