{"title":"Push out bond strength of resin -based endodontic sealer loaded with silver gold nanoparticles in vitro study.","authors":"Nermine Hassan, Mona Riad, Shereen Hafez Ibrahim, Bassam Ahmed Abulnoor, Reham Hassan","doi":"10.1038/s41405-025-00331-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The push-out bond strength to the intraradicular dentin was evaluated in this in vitro study using an epoxy-based endodontic sealer loaded with silver-gold nanoparticles. Additionally, the benefits of using the nanoparticles as a canal pretreatment before applying the sealer were evaluated in comparison to using the sealer alone.</p><p><strong>Methodology: </strong>After being decoronated and instrumented, thirty extracted human central incisors were obturated and then divided horizontally into three parts (coronal, middle, and apical) with a thickness of 2 mm. Three groups of slices were created at random: Groups I (control) and II received AH Plus sealer, AH Plus sealer loaded with silver gold nanoparticles, and III received nanoparticles as a pretreatment for the canal prior to gutta-percha and AH Plus sealer for obturation. The specimens were loaded at a rate of 0.5 mm/min utilizing a Universal Test Machine and put through a push-out test. Statistics were applied to each data collection. Additionally, the significance level was set at P ≤ 0.05.</p><p><strong>Results: </strong>A push-out test showed that the groups differed significantly from one another. The tested groups differed significantly in both the coronal and middle portions, with group (II) exhibiting the highest push-out strength values. Group (II) had the highest push-out strength values in the apical portion (3.66 ± 0.72), followed by group (III) (2.90 ± 1.45), while group (I) had the lowest value (2.88 ± 1.73). There was no significant difference between the groups.</p><p><strong>Conclusions: </strong>the experimental AH Plus sealer combined with silver-gold nanoparticles demonstrated the most effective adhesion followed by nanoparticles as a canal pretreatment prior to sealer application when compared to AH Plus sealer alone.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"11 1","pages":"47"},"PeriodicalIF":2.5000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12062364/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BDJ Open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41405-025-00331-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: The push-out bond strength to the intraradicular dentin was evaluated in this in vitro study using an epoxy-based endodontic sealer loaded with silver-gold nanoparticles. Additionally, the benefits of using the nanoparticles as a canal pretreatment before applying the sealer were evaluated in comparison to using the sealer alone.
Methodology: After being decoronated and instrumented, thirty extracted human central incisors were obturated and then divided horizontally into three parts (coronal, middle, and apical) with a thickness of 2 mm. Three groups of slices were created at random: Groups I (control) and II received AH Plus sealer, AH Plus sealer loaded with silver gold nanoparticles, and III received nanoparticles as a pretreatment for the canal prior to gutta-percha and AH Plus sealer for obturation. The specimens were loaded at a rate of 0.5 mm/min utilizing a Universal Test Machine and put through a push-out test. Statistics were applied to each data collection. Additionally, the significance level was set at P ≤ 0.05.
Results: A push-out test showed that the groups differed significantly from one another. The tested groups differed significantly in both the coronal and middle portions, with group (II) exhibiting the highest push-out strength values. Group (II) had the highest push-out strength values in the apical portion (3.66 ± 0.72), followed by group (III) (2.90 ± 1.45), while group (I) had the lowest value (2.88 ± 1.73). There was no significant difference between the groups.
Conclusions: the experimental AH Plus sealer combined with silver-gold nanoparticles demonstrated the most effective adhesion followed by nanoparticles as a canal pretreatment prior to sealer application when compared to AH Plus sealer alone.