Post-Mohs surgical wounds treated with intact fish skin graft: a multicenter analysis.

IF 1.4 4区 医学 Q3 DERMATOLOGY
Ryan O'Quinn, Courtney Aldridge, David S Sax
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引用次数: 0

Abstract

Background: Intact fish skin graft (IFSG) has been reported to be an adjunct to healing post-Mohs surgical wounds.

Objective: To assess the data that could be found on the use of IFSG in conjunction with Mohs surgery.

Materials and methods: A non-interventional observational registry collected data on the use, indications, and outcomes of IFSG over 32 weeks. This registry collected data on IFSG placed for a broad variety of indications. The primary end point was to determine the percentage of wounds closed at 32 weeks, and the secondary objective was to determine the median number of IFSG applications during this period. The registry was queried for patients who had IFSG placed for wounds created by Mohs surgery.

Results: As of mid-April 2024, 41 participants enrolled in the registry had undergone placement of IFSG post-Mohs surgery. The mean (standard deviation) patient age was 77.6 (8.9) years, and 24% of participants were female (n = 10). Forty of 41 wounds (97.6%) achieved complete wound closure in a median of 5 weeks, and the median number of visits was 5. For closed wounds, the median number of applications was 2.

Conclusion: This registry demonstrates that in a real-world setting, IFSG provides support to aid wound closure. In the post-Mohs setting, only 1 to 2 IFSG applications were required. This study demonstrates how IFSG can be a viable option for Mohs surgeons to consider in the reconstruction paradigm for a variety of wound sizes and anatomic locations.

完整鱼皮移植治疗莫氏术后伤口:多中心分析。
背景:完整鱼皮移植(IFSG)已被报道为治疗莫氏术后伤口的辅助手段。目的:评估IFSG与Mohs手术联合使用的数据。材料和方法:一项非介入性观察登记收集了超过32周IFSG的使用、适应症和结果的数据。该登记处收集了用于各种适应症的IFSG数据。主要终点是确定32周时伤口愈合的百分比,次要目标是确定在此期间IFSG应用的中位数。该登记处查询了因莫氏手术造成的伤口放置IFSG的患者。结果:截至2024年4月中旬,登记的41名参与者在mohs手术后接受了IFSG放置。患者的平均(标准差)年龄为77.6(8.9)岁,24%的参与者为女性(n = 10)。41例创面中有40例(97.6%)创面在5周内完全愈合,中位就诊次数为5次。对于闭合伤口,应用的中位数为2。结论:本研究表明,在现实世界中,IFSG为伤口愈合提供了支持。在mohs后设置中,只需要1到2个IFSG应用程序。这项研究表明,对于Mohs外科医生来说,IFSG是一种可行的选择,可用于各种伤口大小和解剖位置的重建范例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.50
自引率
11.80%
发文量
77
审稿时长
6-12 weeks
期刊介绍: Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.
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