[Investigation of the Usefulness of Intermittent Self-Dilation after Transurethral Surgery for Urethral Stricture].

Q4 Medicine
Tomoya Yokoi, Rikuri Someya, Eriko Tanaka, Mami Yamasaki, Heisuke Iijima, Takehiro Takahashi, Masakatsu Ueda, Yusuke Shiraishi, Koji Yoshimura
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引用次数: 0

Abstract

We retrospectively examined the restenosis rate, factors associated withrestenosis withand without intermittent self-dilatation (ISD) after transurethral surgery for urethral stricture. Male patients diagnosed with urethral stricture between July 2012 and October 2019 who underwent primary treatment by internal urethrotomy or urethral stricture dilatation were divided into two groups : those who received ISD and those who did not. Factors associated with restenosis in the ISD group were also analyzed. The total number of patients analyzed was 45,34 (75.6%) in the ISD group and 11 (24.4%) in the no ISD group. The median age was 71 years. 19 (42.2%) had undergone transurethral surgery, 15 (33.3%) had undergone total prostatectomy, and the majority had undergone urological surgery. The hazard ratio in the ISD group was 0.1894 (95% confidence interval : 0.06749-0.5317, p=0.001), suggesting that ISD significantly increased the time to recurrence. ISD significantly prolonged the time to recurrence. Also, restenosis was significantly more frequent when ISD was performed for less than 5 months (p=0.00723). The results suggest that intermittent self-dilation after transurethral surgery as primary treatment for urethral stricture significantly increases the time to restenosis and that performing the procedure for more than 5 months reduces the rate of restenosis development.

尿道狭窄经尿道手术后间歇性自我扩张术的应用研究
我们回顾性分析了经尿道尿道狭窄手术后再狭窄的发生率,伴有和不伴有间歇性自我扩张(ISD)的再狭窄相关因素。将2012年7月至2019年10月期间经尿道内切开或尿道狭窄扩张治疗的男性尿道狭窄患者分为两组:接受ISD治疗的患者和未接受ISD治疗的患者。分析ISD组再狭窄的相关因素。分析的患者总数为4534例(75.6%),无ISD组11例(24.4%)。中位年龄为71岁。经尿道手术19例(42.2%),全前列腺切除术15例(33.3%),多数行泌尿外科手术。ISD组的危险比为0.1894(95%可信区间:0.06749 ~ 0.5317,p=0.001),表明ISD显著增加了复发时间。ISD明显延长复发时间。此外,ISD手术时间小于5个月时,再狭窄发生率显著增加(p=0.00723)。结果表明,经尿道手术后间歇性自我扩张作为尿道狭窄的主要治疗方法可显著增加再狭窄的时间,且持续5个月以上可降低再狭窄的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Acta Urologica Japonica
Acta Urologica Japonica Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
74
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