Anaemia in pregnancy: can we improve care?

Yang Xuan Cassandra Ang, Stella Rizalina Sasha Sugianto, Desiree Yu Ting Yen, Monica Shi Qi Chua, Kai Zhi Ong, Shu Qi Tan
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Abstract

Introduction: Maternal anaemia is the most common condition in pregnancy. It has profound consequences for both the mother and child, despite being easily treatable with iron supplementation. Our study aimed to investigate its prevalence, risk factors, and the current compliance to screening and treatment.

Methods: Women who delivered a baby between 1 October 2019 and 31 December 2019 at KK Women's and Children's Hospital, Singapore, were included. Haemoglobin levels at booking, 24-28 weeks and delivery were analysed. The frequency of treatment with iron supplementation or blood transfusion was also evaluated. Patient demographics were analysed using descriptive statistical methods, while Pearson's chi-square test was used for analyses of proportions.

Results: The prevalence of maternal anaemia at the time of delivery was 17.2%. Significant risk factors included receiving subsidised healthcare (associated with lower socioeconomic status), teenage pregnancy, multiparity, Indian ethnicity, thalassaemia and antepartum haemorrhage (P < 0.05). Compliance to screening was 62.8% at 24-28 weeks. Only 38.4% of women with anaemia at booking and 74.9% with anaemia at 24-28 weeks were prescribed oral iron. A total of 11.2% of women with maternal anaemia received intravenous iron. The mean haemoglobin level of women who received blood transfusion was 8.3 g/dL, which may not have been appropriate.

Conclusion: Institutions should create guidelines to standardise the screening and treatment of maternal anaemia and conduct regular audits to monitor their implementation. We recommend a multi-pronged strategy targeting prevention, routine screening, and appropriate treatment of maternal anaemia.

妊娠期贫血:我们能改善护理吗?
孕妇贫血是妊娠期最常见的疾病。它对母亲和孩子都有深远的影响,尽管通过补充铁很容易治疗。我们的研究旨在调查其患病率、危险因素以及目前对筛查和治疗的依从性。方法:纳入2019年10月1日至2019年12月31日在新加坡KK妇女儿童医院分娩的妇女。分析预定、24-28周和分娩时的血红蛋白水平。还评估了补铁或输血治疗的频率。患者人口统计学分析采用描述性统计方法,比例分析采用Pearson卡方检验。结果:分娩时产妇贫血率为17.2%。重要的危险因素包括接受医疗补贴(与较低的社会经济地位相关)、少女怀孕、多胎、印度裔、地中海贫血和产前出血(P < 0.05)。24-28周时,筛查依从性为62.8%。只有38.4%的预约贫血妇女和74.9%的24-28周贫血妇女服用口服铁。共有11.2%的孕产妇贫血妇女接受了静脉注射铁。接受输血的妇女的平均血红蛋白水平为8.3 g/dL,这可能不合适。结论:各机构应制定准则,使孕产妇贫血的筛查和治疗标准化,并定期进行审计,以监测其执行情况。我们建议采取多管齐下的策略,以预防、常规筛查和适当治疗孕产妇贫血为目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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