Metabolomics for the Identification of Biomarkers in Kidney Diseases.

Q1 Pharmacology, Toxicology and Pharmaceutics
Nanotheranostics Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI:10.7150/ntno.108320
Swarnima Pandey
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引用次数: 0

Abstract

With the apparent rise in lifestyle-related changes, there has been a significant decline in renal health. Metabolomics plays a crucial role in the prognosis, diagnosis, and treatment of various renal conditions, including chronic kidney disease, acute kidney injury, diabetic kidney disease, kidney cancer, and post-transplant complications. Metabolomics has identified novel biomarkers, providing insights into altered pathways and potential therapeutic targets for kidney diseases. Kidney diseases and metabolomics keywords were searched in correspondence with the assigned keywords, including chronic kidney diseases, acute kidney injury, kidney carcinoma, kidney transplant, and diabetic kidney diseases on literature search engines. The applicable studies from this search were extracted and included in the study. This review is focused on the biomarkers identified in different kidney diseases such as chronic kidney diseases, acute kidney injury, diabetic kidney disease, kidney carcinoma and kidney transplant.

Abstract Image

Abstract Image

代谢组学在肾脏疾病生物标志物鉴定中的应用。
随着与生活方式相关的改变的明显增加,肾脏健康状况明显下降。代谢组学在各种肾脏疾病的预后、诊断和治疗中起着至关重要的作用,包括慢性肾脏疾病、急性肾损伤、糖尿病肾病、肾癌和移植后并发症。代谢组学已经确定了新的生物标志物,为肾脏疾病的改变途径和潜在治疗靶点提供了见解。按照指定的关键词在文献搜索引擎上检索肾脏疾病和代谢组学关键词,包括慢性肾病、急性肾损伤、肾癌、肾移植、糖尿病肾病。从该搜索中提取适用的研究并纳入本研究。本文就慢性肾病、急性肾损伤、糖尿病肾病、肾癌和肾移植等不同肾脏疾病中发现的生物标志物进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nanotheranostics
Nanotheranostics Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
10.40
自引率
0.00%
发文量
37
审稿时长
12 weeks
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