Luciana Pereira de-Sousa, Pamela Rosa-Gonçalves, Beatriz Nogueira Siqueira-E-Silva, Ingrid de Oliveira de-Lavigne, Yuri Chaves Martins, Cláudio Tadeu Daniel-Ribeiro
{"title":"Complementary therapeutic use of exercise in malaria's neurocognitive sequelae.","authors":"Luciana Pereira de-Sousa, Pamela Rosa-Gonçalves, Beatriz Nogueira Siqueira-E-Silva, Ingrid de Oliveira de-Lavigne, Yuri Chaves Martins, Cláudio Tadeu Daniel-Ribeiro","doi":"10.1016/j.pt.2025.04.012","DOIUrl":null,"url":null,"abstract":"<p><p>Malaria can compromise neurocognitive and behavioral integrity. Immunomodulation has been proposed as a mechanism by which exercise benefits brain function, including preventing neurocognitive decline in neurodegenerative diseases. We propose that immunomodulation through moderate-intensity aerobic exercise may be a potential approach to mitigate malaria-related neurocognitive and behavioral alterations.</p>","PeriodicalId":23327,"journal":{"name":"Trends in parasitology","volume":" ","pages":""},"PeriodicalIF":7.0000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in parasitology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.pt.2025.04.012","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PARASITOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Malaria can compromise neurocognitive and behavioral integrity. Immunomodulation has been proposed as a mechanism by which exercise benefits brain function, including preventing neurocognitive decline in neurodegenerative diseases. We propose that immunomodulation through moderate-intensity aerobic exercise may be a potential approach to mitigate malaria-related neurocognitive and behavioral alterations.
期刊介绍:
Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts.
Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.