Jenny J W Liu, Anthony Nazarov, Natalie Ein, Bethany Easterbrook, Tri Le, Clara Baker, Julia Gervasio, Edouard Auger, Ken Balderson, Mathieu Bilodeau, Amer M Burhan, Murray W Enns, Fardous Hosseiny, Vicky Lavoie, Natalie Mota, Maya L Roth, Sonya G Wanklyn, J Don Richardson
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引用次数: 0
Abstract
Background: Military and Veteran populations experience higher rates of posttraumatic stress disorder (PTSD) compared to civilians. While trauma focused psychotherapies are generally recommended as first-line treatments, the effectiveness of various treatments in military populations requires further investigation.
Objective: This meta-analysis aims to synthesize the current literature regarding effectiveness of psychotherapies, pharmacotherapies, and combination treatments for PTSD in military populations.
Data Sources: This preregistered review (PROSPERO: CRD42021245754) was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta Analyses and Cochrane guidelines. A search was conducted using PsycINFO, MEDLINE, Embase, CINAHL, and ProQuest Dissertations and Theses.
Study Selection: The final sample included data from 414 studies.
Data Extraction: Full study methodologies can be found in the published protocol (Liu et al, 2021).
Results: The pooled random-effects model found effect size across all PTSD treatments (k = 712) was g=0.96, compared to g=0.45 for control conditions (k = 122). Clinician administered measures indicated larger treatment effects (g= 1.02) than self reported measures (g =0.82). Combination therapies yielded the largest effects (g =2.17), outperforming both psychotherapies and pharmacotherapies alone. No significant differences were found across control conditions.
Conclusion: Findings suggest that integrating psychotherapies and pharmacotherapies may address multiple dimensions of PTSD more effectively than monotherapies. However, these results contrast with the prioritization of trauma-informed psychotherapies over pharmacotherapies, as recommended by the 2023 US Department of Veterans Affairs/Department of Defense guidelines. Future research should focus on subclass analyses and long-term outcomes to refine treatment strategies for PTSD in military populations. Tailoring treatment plans to individual needs remains crucial for optimizing recovery and long-term symptom management.
期刊介绍：
For over 75 years, The Journal of Clinical Psychiatry has been a leading source of peer-reviewed articles offering the latest information on mental health topics to psychiatrists and other medical professionals.The Journal of Clinical Psychiatry is the leading psychiatric resource for clinical information and covers disorders including depression, bipolar disorder, schizophrenia, anxiety, addiction, posttraumatic stress disorder, and attention-deficit/hyperactivity disorder while exploring the newest advances in diagnosis and treatment.
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