A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization.
{"title":"A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization.","authors":"Rui Wang, Yongjiang Chen, Chudong Wang, Zijian Li, Yunpeng Zhong, Yunjuan Liang, Shuben Li","doi":"10.21037/tlcr-24-901","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Pulmonary nodules are the most common manifestation of lung cancer. The detection rate of multiple nodules has been increasing and it is essential to figure out a precise way for localization of the nodules. The purpose of this study is to evaluate the efficacy, accuracy and safety of electromagnetic navigation bronchoscopy (ENB)-guided dye marking for localizing multiple ipsilateral nodules compared with computed tomography (CT)-guided lung puncture.</p><p><strong>Methods: </strong>We performed a retrospective cohort study of patients with multiple nodules in the ipsilateral lung who received preoperative localization [including ENB-guided dye marking (ENBDM) or CT-guided lung puncture] and video-assisted thoracoscopic surgery between September 2018 and April 2023. Data were statistically analyzed and visualized using SPSS v25.0 and Microsoft Excel 2019 software.</p><p><strong>Results: </strong>A total of 203 patients were evaluated, among whom 99 underwent ENBDM to localize nodules preoperatively, and 104 were located by CT-guided lung puncture. In terms of localization time, ENB group compared with CT group consumed less time (8.00±4.66 <i>vs.</i> 22.00±8.82 min, P<0.001). In the ENB group, compared with the CT group, there was no radiation exposure. No related complications occurred in the ENB group, including pleural reaction [0 <i>vs.</i> 8 (7.7%), P=0.01], pneumothorax [0 <i>vs.</i> 36 (34.6%), P<0.001], and hemothorax [0 <i>vs.</i> 15 (14.4%), P<0.001]. However, no significant differences were observed in the success localization rate (97.4% <i>vs.</i> 94.9%, P=0.48) between the two groups.</p><p><strong>Conclusions: </strong>For patients with multiple ipsilateral pulmonary nodules, ENBDM can achieve the similar localization accuracy as CT-guided lung puncture, with shorter localization time and no complications. ENBDM is a safe and effective preoperative localization method for multiple ipsilateral pulmonary nodules.</p>","PeriodicalId":23271,"journal":{"name":"Translational lung cancer research","volume":"14 3","pages":"775-784"},"PeriodicalIF":4.0000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12000950/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational lung cancer research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/tlcr-24-901","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/27 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Pulmonary nodules are the most common manifestation of lung cancer. The detection rate of multiple nodules has been increasing and it is essential to figure out a precise way for localization of the nodules. The purpose of this study is to evaluate the efficacy, accuracy and safety of electromagnetic navigation bronchoscopy (ENB)-guided dye marking for localizing multiple ipsilateral nodules compared with computed tomography (CT)-guided lung puncture.
Methods: We performed a retrospective cohort study of patients with multiple nodules in the ipsilateral lung who received preoperative localization [including ENB-guided dye marking (ENBDM) or CT-guided lung puncture] and video-assisted thoracoscopic surgery between September 2018 and April 2023. Data were statistically analyzed and visualized using SPSS v25.0 and Microsoft Excel 2019 software.
Results: A total of 203 patients were evaluated, among whom 99 underwent ENBDM to localize nodules preoperatively, and 104 were located by CT-guided lung puncture. In terms of localization time, ENB group compared with CT group consumed less time (8.00±4.66 vs. 22.00±8.82 min, P<0.001). In the ENB group, compared with the CT group, there was no radiation exposure. No related complications occurred in the ENB group, including pleural reaction [0 vs. 8 (7.7%), P=0.01], pneumothorax [0 vs. 36 (34.6%), P<0.001], and hemothorax [0 vs. 15 (14.4%), P<0.001]. However, no significant differences were observed in the success localization rate (97.4% vs. 94.9%, P=0.48) between the two groups.
Conclusions: For patients with multiple ipsilateral pulmonary nodules, ENBDM can achieve the similar localization accuracy as CT-guided lung puncture, with shorter localization time and no complications. ENBDM is a safe and effective preoperative localization method for multiple ipsilateral pulmonary nodules.
期刊介绍：
Translational Lung Cancer Research(TLCR, Transl Lung Cancer Res, Print ISSN 2218-6751; Online ISSN 2226-4477) is an international, peer-reviewed, open-access journal, which was founded in March 2012. TLCR is indexed by PubMed/PubMed Central and the Chemical Abstracts Service (CAS) Databases. It is published quarterly the first year, and published bimonthly since February 2013. It provides practical up-to-date information on prevention, early detection, diagnosis, and treatment of lung cancer. Specific areas of its interest include, but not limited to, multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
