Impact of intramedullary pinning and recombinant human bone morphogenetic protein-2 on postoperative complications after proximal ulnar osteotomy in dogs.

IF 1.3 2区 农林科学 Q2 VETERINARY SCIENCES
Alan Danielski, Holly A Wilson, Miguel A Solano
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Abstract

Objective: To evaluate the complication rate following proximal ulnar osteotomy (PUO) performed in conjunction with the use of an intramedullary pin and bone morphogenetic proteins in dogs, and to assess the impact of these variables on surgical outcomes.

Study design: Retrospective study.

Sample population: A total of 93 limbs (74 dogs).

Methods: Medical records and radiographs of dogs that underwent oblique PUO with intramedullary pin and recombinant human bone morphogenetic protein-2 (rhBMP-2) application between January 2022 and June 2024 were reviewed. Data collected included breed, age, weight, surgical indication, and postoperative complications, classified as minor or major. Radiographic assessments were performed to evaluate bone healing 6 weeks after surgery.

Results: Follow-up examination and radiographs were performed in all cases at a mean time of 6 ± 1.1 weeks after surgery. The overall complication rate was 7.4%, with major complications, primarily surgical site infections (4 out of 5 cases), occurring in five of 93 limbs (5.3%). Minor complications, including seroma and delayed union, were observed in two of 93 limbs (2.1%). No cases of non-union were documented, with 92/93 limbs achieving radiographic healing within the expected timeframe. A total of 48 (64.8%) of the dogs treated were chondrodystrophic breeds, historically considered at high risk of complications.

Conclusion: The combined use of an intramedullary pin and rhBMP-2 was associated with low complication rates and enhanced bone healing, even in chondrodystrophic breeds.

Clinical significance: This study supports the use of an intramedullary pin and rhBMP-2 in PUO as a safe and effective strategy to minimize complications, including in high-risk breeds.

髓内钉钉和重组人骨形态发生蛋白-2对犬尺近端截骨术后并发症的影响。
目的:评估犬近端尺侧截骨术(PUO)联合髓内针和骨形态发生蛋白的并发症发生率,并评估这些变量对手术结果的影响。研究设计:回顾性研究。样本种群:共93只肢体(74只犬)。方法:回顾性分析2022年1月至2024年6月间采用髓内针和重组人骨形态发生蛋白-2 (rhBMP-2)应用斜向PUO的犬的病历和x线片。收集的数据包括品种、年龄、体重、手术指征和术后并发症,分为轻微或严重。术后6周行影像学评估骨愈合情况。结果:所有病例均在术后平均6±1.1周进行随访检查和x线片检查。总并发症发生率为7.4%,主要并发症以手术部位感染为主(5例中有4例),93例肢体中有5例发生(5.3%)。93个肢体中有2个(2.1%)出现轻微并发症,包括血肿和延迟愈合。未发现骨不连病例,92/93例患者在预期时间内实现了影像学愈合。共有48只(64.8%)接受治疗的狗是软骨营养不良的品种,历史上被认为是并发症的高风险品种。结论:髓内针和rhBMP-2联合使用可降低并发症发生率,促进骨愈合,即使在软骨营养不良的品种中也是如此。临床意义:本研究支持髓内针和rhBMP-2作为一种安全有效的策略来减少PUO并发症,包括在高风险品种中。
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来源期刊
Veterinary Surgery
Veterinary Surgery 农林科学-兽医学
CiteScore
3.40
自引率
22.20%
发文量
162
审稿时长
8-16 weeks
期刊介绍: Veterinary Surgery, the official publication of the American College of Veterinary Surgeons and European College of Veterinary Surgeons, is a source of up-to-date coverage of surgical and anesthetic management of animals, addressing significant problems in veterinary surgery with relevant case histories and observations. It contains original, peer-reviewed articles that cover developments in veterinary surgery, and presents the most current review of the field, with timely articles on surgical techniques, diagnostic aims, care of infections, and advances in knowledge of metabolism as it affects the surgical patient. The journal places new developments in perspective, encompassing new concepts and peer commentary to help better understand and evaluate the surgical patient.
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