Increased Risk of Suicide Attempt in Patients With Atopic Dermatitis: A Nationwide Population-Based Cohort Study.

IF 4.5 2区医学 Q1 PSYCHIATRY

Journal of Clinical Psychiatry Pub Date : 2025-05-05 DOI:10.4088/JCP.24m15590

Mu-Chun Lin, Sheng-Hsiang Ma, Ying-Hsuan Tai, Ying-Xiu Dai, Mu-Hong Chen, Chih-Chiang Chen

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引用次数: 0

Abstract

Introduction: Atopic dermatitis (AD) is associated with an increased risk of mental illness. However, few studies have explored the association between AD and suicidal risk. This study aimed to investigate the risk of suicide attempts in patients with AD.

Methods: Between 1997-2013, 5,169 patients with AD and 20,676 controls (1:4) matched according to age, sex, socioeconomic status, and selected comorbidities were enrolled from the Taiwan's National Health Insurance Research Database to analyze the risk of suicide attempt.

Results: Individuals with AD were found to have an elevated risk of suicide attempts, with an adjusted hazard ratio of 3.44 (95% CI, 1.83-6.46), compared to the control group. In the stratification analysis, the risk of suicide remained significantly higher in patients with AD of younger age, female sex, and those with cumulative systemic corticosteroid use for <30 days.

Conclusions: Dermatologists must recognize the potential increased suicidal risk in patients with AD, especially in vulnerable groups and those with certain comorbidities. Furthermore, patients with mild AD did not have a reduced suicidal risk.

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特应性皮炎患者自杀企图风险增加：一项全国性人群队列研究

引言：特应性皮炎（AD）与精神疾病的风险增加有关。然而，很少有研究探讨阿尔茨海默病和自杀风险之间的关系。本研究旨在调查阿尔茨海默病患者自杀企图的风险。结果：与对照组相比，AD患者有较高的自杀企图风险，调整后的风险比为3.44 （95% CI, 1.83-6.46）。在分层分析中，年龄较小、女性和累积全身性使用皮质类固醇的阿尔茨海默病患者的自杀风险仍然明显较高。结论：皮肤科医生必须认识到阿尔茨海默病患者自杀风险的潜在增加，特别是在弱势群体和有某些合并症的人群中。此外，轻度AD患者的自杀风险并没有降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Psychiatry 医学-精神病学

CiteScore

7.40

自引率

1.90%

发文量

审稿时长

3-8 weeks

期刊介绍： For over 75 years, The Journal of Clinical Psychiatry has been a leading source of peer-reviewed articles offering the latest information on mental health topics to psychiatrists and other medical professionals.The Journal of Clinical Psychiatry is the leading psychiatric resource for clinical information and covers disorders including depression, bipolar disorder, schizophrenia, anxiety, addiction, posttraumatic stress disorder, and attention-deficit/hyperactivity disorder while exploring the newest advances in diagnosis and treatment.