Predictive value of triglyceride glucose index and systemic inflammation index for diabetic retinopathy in Type-2 diabetes.

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Jie Li, Yanling Li, Qiannan Qi, Na Chen, Yueling Zhang
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Abstract

Objective: To explore the predictive efficacy of the triglyceride glucose (TyG) index and systemic immune inflammation index (SII) levels for diabetic retinopathy (DR) in patients with Type-2 diabetes mellitus (T2DM).

Methods: A retrospective study was conducted on 200 T2DM patients admitted to the Ophthalmology Department at Baoding No.1 Central Hospital from June 2023 to December 2023. The patients were divided into 80 none-DR, 120 with DR. General information, biochemical tests, TyG index, and SII were collected. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive ability of TyG index and SII for DR. Binary logistic regression was employed to assess the relationship between DR occurrence and TyG index and SII.

Results: The mean TyG index and SII levels were higher in the DR group compared to none-DR group (P<0.05). The ROC curve analysis indicated that the combination of TyG index and SII had the highest area under the curve (AUC) at 0.912, surpassing the AUC of TyG index and SII individually. Binary logistic regression analysis demonstrated that TyG index and SII were independent predictors of DR occurrence in diabetic patients (OR=1.745, 95%CI: 1.213-2.547, P<0.05; OR=1.347, 95%CI: 1.115-1.843, P<0.05, respectively).

Conclusion: TyG index and SII levels may predict the occurrence of DR in T2DM patients, and the combination of these two indices offers the best predictive efficacy for DR.

甘油三酯葡萄糖指数和全身炎症指数对2型糖尿病视网膜病变的预测价值。
目的:探讨甘油三酯葡萄糖(TyG)指数和全身免疫炎症指数(SII)水平对2型糖尿病(T2DM)患者糖尿病视网膜病变(DR)的预测作用。方法:对2023年6月至2023年12月在保定市第一中心医院眼科就诊的200例T2DM患者进行回顾性研究。将患者分为无dr 80例和dr 120例,收集患者一般资料、生化指标、TyG指数、SII指数。采用受试者工作特征(Receiver operating characteristic, ROC)曲线分析评价TyG指数和SII对DR的预测能力,采用二元logistic回归评估DR发生与TyG指数和SII的关系。结果:DR组TyG指数和SII水平均值高于非DR组(ppp)结论:TyG指数和SII水平可预测T2DM患者DR的发生,且两者联合预测DR的效果最好。
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来源期刊
Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences 医学-医学:内科
CiteScore
4.10
自引率
9.10%
发文量
363
审稿时长
3-6 weeks
期刊介绍: It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.
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