Jie Li, Yanling Li, Qiannan Qi, Na Chen, Yueling Zhang
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引用次数: 0
Abstract
Objective: To explore the predictive efficacy of the triglyceride glucose (TyG) index and systemic immune inflammation index (SII) levels for diabetic retinopathy (DR) in patients with Type-2 diabetes mellitus (T2DM).
Methods: A retrospective study was conducted on 200 T2DM patients admitted to the Ophthalmology Department at Baoding No.1 Central Hospital from June 2023 to December 2023. The patients were divided into 80 none-DR, 120 with DR. General information, biochemical tests, TyG index, and SII were collected. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive ability of TyG index and SII for DR. Binary logistic regression was employed to assess the relationship between DR occurrence and TyG index and SII.
Results: The mean TyG index and SII levels were higher in the DR group compared to none-DR group (P<0.05). The ROC curve analysis indicated that the combination of TyG index and SII had the highest area under the curve (AUC) at 0.912, surpassing the AUC of TyG index and SII individually. Binary logistic regression analysis demonstrated that TyG index and SII were independent predictors of DR occurrence in diabetic patients (OR=1.745, 95%CI: 1.213-2.547, P<0.05; OR=1.347, 95%CI: 1.115-1.843, P<0.05, respectively).
Conclusion: TyG index and SII levels may predict the occurrence of DR in T2DM patients, and the combination of these two indices offers the best predictive efficacy for DR.
期刊介绍:
It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad.
Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.