[MSB-70] Prognostic Value of the Hemoglobin, Albumin, Lymphocyte, Platelet Score in Predicting One-Year Mortality and Complications in Patients Undergoing Isolated Coronary Artery Bypass Grafting.
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引用次数: 0
Abstract
Objective: This study aimed to investigate the relationship between the hemoglobin, albumin, lymphocyte, platelet (HALP) score, a novel scoring system that reflects systemic inflammation, and one-year mortality and complications in patients undergoing coronary artery bypass grafting (CABG).
Methods: The retrospective study included 359 consecutive patients (287 males, 72 females; mean age: 60.9 years) diagnosed with coronary artery disease who underwent CABG between January 2020 and February 2023. Patients with concomitant mitral valve replacement, aortic surgery, carotid endarterectomy, aortofemoral bypass, intracardiac tumor excision, mediastinal tumor excision, or those who underwent emergency or urgent procedures were excluded from the study. The patients were divided into two groups based on a HALP score cutoff value of 34.1. Group 1 included patients with a HALP score lower than the cutoff value, while Group 2 included those with a HALP score higher than the cutoff value.
Results: The one-year mortality rate was significantly higher in Group 1 compared to Group 2 (16% vs. 5%). Additionally, rates of major adverse cardiovascular and cerebrovascular events, atrial fibrillation, high-dose inotropic support, pneumonia, pleural effusion, prolonged intubation, acute kidney injury, cerebrovascular events, and length of stay in both the intensive care unit and hospital were significantly higher in Group 1 than in Group 2.
Conclusion: The findings of our study indicate that the HALP score can be used to assess one-year mortality and complication risks in patients undergoing isolated CABG. However, to establish it as an independent factor, further analyses with a larger patient population are warranted.
目的:本研究旨在探讨反映全身性炎症的新型评分系统——血红蛋白、白蛋白、淋巴细胞、血小板(HALP)评分与冠状动脉旁路移植术(CABG)患者一年死亡率和并发症之间的关系。方法:回顾性研究纳入359例连续患者(男性287例,女性72例;平均年龄:60.9岁),诊断为冠状动脉疾病,在2020年1月至2023年2月期间接受了冠脉搭桥。同时行二尖瓣置换术、主动脉手术、颈动脉内膜切除术、主动脉搭桥术、心内肿瘤切除术、纵隔肿瘤切除术或接受急诊或紧急手术的患者被排除在研究之外。根据HALP评分临界值34.1将患者分为两组。组1为HALP评分低于临界值的患者,组2为HALP评分高于临界值的患者。结果:1组的1年死亡率明显高于2组(16% vs. 5%)。此外,1组的主要不良心脑血管事件、心房颤动、大剂量肌力支持、肺炎、胸腔积液、延长插管时间、急性肾损伤、脑血管事件以及在重症监护室和医院的住院时间的发生率均显著高于2组。结论:我们的研究结果表明,HALP评分可用于评估孤立性冠脉搭桥患者的1年死亡率和并发症风险。然而,为了确定它是一个独立的因素,需要对更大的患者群体进行进一步的分析。
期刊介绍:
The Turkish Journal of Thoracic and Cardiovascular Surgery is an international open access journal which publishes original articles on topics in generality of Cardiac, Thoracic, Arterial, Venous, Lymphatic Disorders and their managements. These encompass all relevant clinical, surgical and experimental studies, editorials, current and collective reviews, technical know-how papers, case reports, interesting images, How to Do It papers, correspondences, and commentaries.