Comparison of the Aperio Hybrid® and Solitaire FR/X® stents for anterior circulation stroke thrombectomy across different time periods: A propensity score-matched analysis of recanalization and symptomatic hemorrhage.

IF 1.5 4区 医学 Q4 CLINICAL NEUROLOGY
Luís Henrique de Castro-Afonso, Felipe Padovani Trivelato, Eduardo Wajnberg, Eduardo Siqueira Waihrich, Thiago Giansante Abud, Saulo Villas Boas Alves, Anderson Matsubara, Marco Tulio Salles Rezende, João Francisco Santoro Araujo, Guilherme Seizem Nakiri, Daniel Giansante Abud
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引用次数: 0

Abstract

IntroductionThrombectomy has become the standard treatment for acute ischemic stroke (AIS) caused by large vessel occlusions (LVOs). The Aperio Hybrid (Acandis, Pforzheim, Germany) is a new stent retriever designed to enhance the effectiveness of this treatment. However, this new stent has not yet been compared to other thrombectomy devices in a clinical setting. The aim of this study was to compare the Aperio Hybrid® with the Solitaire™ FR/X (Medtronic, Minneapolis, USA) during thrombectomy in patients with AIS due to anterior circulation LVO.Materials and methodsWe analyzed data from a multicenter registry of thrombectomy for anterior circulation LVO. Patients with carotid/M1 or proximal M2 occlusions who underwent thrombectomy with either the Aperio Hybrid® or Solitaire™ FR/X® were compared using propensity-score matching (PSM). The primary outcome was the recanalization rate, measured by the Treatment in Cerebral Ischemia (TICI) score of 2b-3, while the secondary outcome was the rate of symptomatic intracranial hemorrhage (sICH).ResultsAmong 455 patients treated, after PSM, 258 patients (129 per group) were analyzed. The adjusted recanalization rates (TICI 2b-3) for the Aperio Hybrid and Solitaire FR/X were 79.8% and 75.9%, respectively (p = .08), while the adjusted sICH rates were 6.9% and 6.2%, respectively (p = .80).ConclusionsIn this observational study on thrombectomy for AIS, the Aperio Hybrid and Solitaire FR/X demonstrated similar rates of recanalization and symptomatic intracranial hemorrhage. However, due to significant selection bias, these results should be interpreted with caution.

Aperio Hybrid®和Solitaire FR/X®支架在不同时期用于前循环卒中血栓切除术的比较:再通和症状性出血的倾向评分匹配分析。
血栓切除术已成为大血管闭塞(LVOs)引起的急性缺血性卒中(AIS)的标准治疗方法。Aperio Hybrid (Acandis, Pforzheim, Germany)是一种新型支架回收器,旨在提高这种治疗的有效性。然而,这种新型支架尚未在临床环境中与其他取栓装置进行比较。本研究的目的是比较Aperio Hybrid®和Solitaire™FR/X (Medtronic, Minneapolis, USA)在前循环LVO引起的AIS患者取栓期间的效果。材料和方法我们分析了来自多中心登记的前循环LVO取栓的数据。使用Aperio Hybrid®或Solitaire™FR/X®进行血栓切除术的颈动脉/M1或M2近端闭塞患者使用倾向评分匹配(PSM)进行比较。主要终点是脑缺血治疗(TICI)评分为2b-3的再通率,次要终点是症状性颅内出血(sICH)的发生率。结果455例患者经PSM治疗后,共分析258例(每组129例)。Aperio Hybrid和Solitaire FR/X调整后的再通率(tici2b -3)分别为79.8%和75.9% (p = 0.08),调整后的siich率分别为6.9%和6.2% (p = 0.80)。结论在这项AIS血栓切除术的观察性研究中,Aperio Hybrid和Solitaire FR/X显示出相似的再通率和症状性颅内出血。然而,由于显著的选择偏差,这些结果应谨慎解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Interventional Neuroradiology
Interventional Neuroradiology CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
3.60
自引率
11.80%
发文量
192
审稿时长
6-12 weeks
期刊介绍: Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...
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