Breastfeeding in HIV-positive mothers under optimized conditions: 'real-life' results from a well-resourced healthcare setting.

IF 1.7 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Perinatal Medicine Pub Date : 2025-04-22 DOI:10.1515/jpm-2025-0170

Cornelia Feiterna-Sperling, Renate Krüger, Hannah Bethke, Jan-Peter Siedentopf, Katharina von Weizsäcker, Michaela Heinrich-Rohr, Irena Rohr

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引用次数: 0

Abstract

Objectives: Global guidelines increasingly support breastfeeding among women living with HIV (WLWH) under optimized conditions. However, outcome data from high-resource settings remain limited.

Methods: We retrospectively analyzed WLWH who delivered at Charité - Universitätsmedizin Berlin between 2017 and 2023. Eligibility for breastfeeding required VL<50 cop/mL.

Results: Of 409 WLWH, 365 (89.2 %) were eligible and 77 (18.8 %) initiated breastfeeding. No case of mother-to-child transmission (MTCT) was observed. Sustained viral suppression and ART adherence were key. Exclusive breastfeeding was associated with longer duration (p=0.001), midwifery care promoted exclusivity (p=0.009), and vaginal delivery was linked to longer duration (p=0.005).

Conclusions: Breastfeeding with VL<50 cop/mL appears safe in high-resource settings. Findings support individualized counseling, close monitoring, and multidisciplinary care. The increasing breastfeeding trend reflects a shift in clinical practice.

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优化条件下艾滋病毒阳性母亲的母乳喂养：资源充足的卫生保健环境的“现实生活”结果。

目标：全球指南越来越多地支持在优化条件下艾滋病毒感染者（WLWH）母乳喂养。然而，来自高资源环境的结果数据仍然有限。方法：回顾性分析2017年至2023年在柏林慈善医院Universitätsmedizin分娩的WLWH。结果：在409名产妇中，365名（89.2% %）符合条件，77名（18.8% %）开始母乳喂养。未观察到母婴传播（MTCT）病例。持续的病毒抑制和抗逆转录病毒疗法的坚持是关键。纯母乳喂养与持续时间更长相关（p=0.001），助产护理促进了母乳喂养（p=0.009），阴道分娩与持续时间更长相关（p=0.005）。结论：母乳喂养与VL

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatal Medicine 医学-妇产科学

CiteScore

4.40

自引率

8.30%

发文量

183

审稿时长

4-8 weeks

期刊介绍： The Journal of Perinatal Medicine (JPM) is a truly international forum covering the entire field of perinatal medicine. It is an essential news source for all those obstetricians, neonatologists, perinatologists and allied health professionals who wish to keep abreast of progress in perinatal and related research. Ahead-of-print publishing ensures fastest possible knowledge transfer. The Journal provides statements on themes of topical interest as well as information and different views on controversial topics. It also informs about the academic, organisational and political aims and objectives of the World Association of Perinatal Medicine.