{"title":"A bioinformatics-driven CURE extension increases student self-efficacy and interest in biomedical research.","authors":"Héctor G Loyola Irizarry, Hiram Duarte, Kyoko Nakamura, Rocio Benabentos, Melissa McCartney, Jessica Siltberg-Liberles","doi":"10.1128/jmbe.00231-24","DOIUrl":null,"url":null,"abstract":"<p><p>The biology workforce has a need for undergraduate students trained in bioinformatics. Although bioinformatics is a critical sub-discipline of biology, it is not required in all biology degree programs. In parallel, there is a need to increase student access to research experiences. To address these needs, we offer a one-credit bioinformatics-focused and computational biology course-based undergraduate research experience (CURE), here called the CB-CURE. Preliminary data suggest the CB-CURE increased student interest, knowledge, and self-efficacy, but also reveal a shortage of access to undergraduate research experiences (UREs) in faculty labs at our large institution. To provide a more URE-like experience for a class setting, we developed a one-semester extension to the CB-CURE, called CURE+. In CURE+, students execute individual bioinformatics-driven research projects and obtain additional career development and mentoring. To evaluate CURE+, we measured students' bioinformatics and research self-efficacy, interest in bioinformatics and research, and emotions toward their project. Additionally, we evaluated student mastery of the CURE+ learning outcomes to determine if the experience successfully enabled students to develop their research skills. Our data show significant increases in (i) student self-efficacy in various bioinformatics and research skills and (ii) student interest in bioinformatics-related activities and in biomedical research. Students had positive emotions toward their research project, and a majority of students mastered the CURE+ learning outcomes. Our data suggest that an intensive CURE extension can provide a potentially transformative research experience that helps fill a void in access to research at institutions with a high student-to-faculty ratio.</p>","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":" ","pages":"e0023124"},"PeriodicalIF":1.6000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Microbiology & Biology Education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/jmbe.00231-24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"EDUCATION, SCIENTIFIC DISCIPLINES","Score":null,"Total":0}
引用次数: 0
Abstract
The biology workforce has a need for undergraduate students trained in bioinformatics. Although bioinformatics is a critical sub-discipline of biology, it is not required in all biology degree programs. In parallel, there is a need to increase student access to research experiences. To address these needs, we offer a one-credit bioinformatics-focused and computational biology course-based undergraduate research experience (CURE), here called the CB-CURE. Preliminary data suggest the CB-CURE increased student interest, knowledge, and self-efficacy, but also reveal a shortage of access to undergraduate research experiences (UREs) in faculty labs at our large institution. To provide a more URE-like experience for a class setting, we developed a one-semester extension to the CB-CURE, called CURE+. In CURE+, students execute individual bioinformatics-driven research projects and obtain additional career development and mentoring. To evaluate CURE+, we measured students' bioinformatics and research self-efficacy, interest in bioinformatics and research, and emotions toward their project. Additionally, we evaluated student mastery of the CURE+ learning outcomes to determine if the experience successfully enabled students to develop their research skills. Our data show significant increases in (i) student self-efficacy in various bioinformatics and research skills and (ii) student interest in bioinformatics-related activities and in biomedical research. Students had positive emotions toward their research project, and a majority of students mastered the CURE+ learning outcomes. Our data suggest that an intensive CURE extension can provide a potentially transformative research experience that helps fill a void in access to research at institutions with a high student-to-faculty ratio.