Ovarian Tumors during Pregnancy and Adverse Pregnancy Outcome: A Retrospective Analysis.

Q2 Medicine

Asian Pacific Journal of Cancer Prevention Pub Date : 2025-04-01 DOI:10.31557/APJCP.2025.26.4.1329

Kittiya Ritta, Wiyada Luangdansakul, Buppa Smanchat, Kornkarn Bhamarapravatana, Komsun Suwannarurk

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引用次数: 0

Abstract

Objective: To determine the prevalence of ovarian tumor in pregnancy.

Materials and methods: A retrospective descriptive study was conducted using electronic data from Obstetrics and Gynecology Department at Bhumibol Adulyadej Hospital (BAH), Royal Thai Air Force, Thailand recorded between January 2012 and December 2022. The participants were patients diagnosed with ovarian tumors during pregnancy (OTP) within the study period. Demographic characteristics, histopathological findings, ultrasonography results and pregnancy outcomes were recorded.

Results: A total of 190 OTP cases were identified among 41,842 pregnant women. One hundred twenty-six OTP cases underwent surgery during pregnancy. The mean age of the participants was 29.6 years. The prevalence of ovarian tumors was 4.5(190/41,842) in 1000 pregnancies. Malignant ovarian tumors accounted for 0.14% (2/126). Histopathological analysis revealed that germ cell ovarian tumors and common epithelial ovarian tumors were found in 50.79% (64/126) and 49.2% (62/126) of cases, respectively. Most germ cell ovarian tumors were mature cystic teratomas, which were found in 98% (63/64) of cases. One-third (32/126) of the OTP cases underwent surgery during the second and early third trimesters. Fetal loss following surgery occurred in 18.75% (6/32) of cases. Adnexectomy performed with cesarean delivery and after vaginal delivery occurred in 93 and 1 cases, respectively. Symptomatic OTP leading to emergency surgery was observed in 6.84% (13/190) of cases.

Conclusion: The prevalence of OTP was 4.5 per 1,000 pregnant women. Fetal loss during surgery in pregnancy occurred in 18.75%. Mature cystic teratoma was the common histopathological finding.

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妊娠期卵巢肿瘤和不良妊娠结局：回顾性分析。

目的：了解妊娠期卵巢肿瘤的发病率。材料和方法：采用2012年1月至2022年12月期间泰国皇家泰国空军普密蓬·阿杜德医院（BAH）妇产科的电子数据进行回顾性描述性研究。参与者是在研究期间诊断为妊娠期间卵巢肿瘤（OTP）的患者。记录人口统计学特征、组织病理学表现、超声检查结果和妊娠结局。结果：41842例孕妇中共发现OTP 190例。126例OTP患者在怀孕期间接受了手术。参与者的平均年龄为29.6岁。卵巢肿瘤的患病率为4.5(190/ 41842)/ 1000次妊娠。卵巢恶性肿瘤占0.14%（2/126）。卵巢生殖细胞肿瘤占50.79%(64/126)，卵巢普通上皮性肿瘤占49.2%（62/126）。卵巢生殖细胞瘤多为成熟囊性畸胎瘤，占98%（63/64）。三分之一（32/126）的OTP病例在妊娠中期和晚期早期接受了手术。18.75%（6/32）的病例发生术后胎儿丢失。剖宫产时行附件切除术93例，阴道分娩后行附件切除术1例。6.84%（13/190）的病例出现症状性OTP导致急诊手术。结论：OTP患病率为4.5 / 1000。妊娠手术中胎儿丢失的发生率为18.75%。成熟囊性畸胎瘤是常见的组织病理学发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Pacific Journal of Cancer Prevention 医学-肿瘤学

CiteScore

2.80

自引率

0.00%

发文量

779

审稿时长

3 months

期刊介绍： Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.