[Area strain as prognostic factor of functional recovering in myocardial infarction].

Joaquín Ahumada-Pérez, Luis Antonio Moreno-Ruíz, Carlos García-Cosío, Ivan Silvestre-Flores, Antonio Ruíz-Rivera, Noe Fernando Zamorano-Velázquez, Guadalupe Cleva Villanueva-López
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Abstract

Background: Area strain evaluates the longitudinal and circumferential deformation simultaneously. There are not estudies that support its benefit in predicting functional recovering in myocardial infarction.

Objective: The aim was establish the prognostic value of the area strain measured within the first 7 days after succesful angioplasty to predicting functional recovering.

Materail and methods: A prospective cohort study was performed during 3-month follow-up. Patients with myocardial infarction treated with succesful angioplasty were enrolled. The area strain was perfomed within the first 7 days. Functional recovering was defined as an improvement of the ejection fraction ≥ 10% at 3-months follow-up.

Results: A total of 52 patients were enrolled. An area strain of ≤ -24.2 % appeared in the 45.5% of the patients with functional recovering, RR 16.25 (IC 95%: 2.55-103, p = 0.003). In the multivariate analyses the area strain of ≤ -24.2 % was the only variable with statistical significance with an OR of 13.15 (IC 95%: 1.83-94, p = 0.010) when was adjusted to hypertension, OR of 12.7 (IC 95%: 1.88-85.9, p = 0.009) adjusted to reperfusion time of ≤ 120 minutes and the OR was of 11.87 (IC 95%: 1.66-84.5, p = 0.013) adjusted to smoking.

Conclusions: An area strain of ≤ - 24.2% is a prognostic factor of improvement of ejection fraction of ≥ 10% at 3-months follow-up in patients with myocardial infarction and succesful angioplasty.

[面积应变作为心肌梗死功能恢复的预后因素]。
背景:区域应变同时评价纵向和周向变形。没有研究支持其在预测心肌梗死功能恢复方面的益处。目的:探讨血管成形术成功后7天内测量的面积应变对预测功能恢复的预测价值。材料和方法:前瞻性队列研究进行了为期3个月的随访。接受血管成形术成功治疗的心肌梗死患者被纳入研究。前7天进行面积应变。功能恢复定义为3个月随访时射血分数改善≥10%。结果:共入组52例患者。45.5%的功能恢复患者出现面积应变≤- 24.2%,RR为16.25 (IC 95%: 2.55 ~ 103, p = 0.003)。多因素分析中,面积应变≤- 24.2%是唯一有统计学意义的变量,高血压校正时OR为13.15 (IC 95%: 1.83 ~ 94, p = 0.010),再灌注时间≤120分钟校正时OR为12.7 (IC 95%: 1.88 ~ 85.9, p = 0.009),吸烟校正时OR为11.87 (IC 95%: 1.66 ~ 84.5, p = 0.013)。结论:面积应变≤- 24.2%是心肌梗死和血管成形术成功患者3个月随访时射血分数改善≥10%的预后因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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