Country-Specific Data and Priorities for Pertussis in Latin America: Recent Findings From the Global Pertussis Initiative.

IF 3.8 4区 医学 Q2 IMMUNOLOGY
Open Forum Infectious Diseases Pub Date : 2025-05-13 eCollection Date: 2025-05-01 DOI:10.1093/ofid/ofaf154
Rolando Ulloa-Gutierrez, Daniela Hozbor, María L Avila-Aguero, Gabriela Echániz-Aviles, Angela Gentile, Juan Pablo Torres Torretti, Ulrich Heininger, Rudzani Muloiwa, Carl Heinz Wirsing von König, Kevin Forsyth, Tina Q Tan
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引用次数: 0

Abstract

In 2023, the Global Pertussis Initiative met to assess the burden of and vaccination policies against pertussis in 10 Latin American countries. Although pertussis is a notifiable disease in the represented countries, poor disease awareness, underrecognition in older individuals, and limited laboratory capacity and supplies challenge the collection of robust epidemiological data. Infants in all 10 countries receive a 3-dose primary series followed by ≥2 boosters. Except for Paraguay and Venezuela, governments of the represented countries advise or mandate vaccination in pregnancy; however, coverage rates remain suboptimal. Healthcare providers and the public should be educated on how mothers and other contacts can serve as asymptomatic carriers of Bordetella pertussis (transmitting disease to vulnerable infants) and of the potentially unique presentation of pertussis in adolescents and adults. The burden of pertussis in Latin America can be reduced by improving vaccination coverage of the primary series, increasing vaccination in pregnancy, and instituting universal vaccination of adults.

拉丁美洲百日咳的国家特定数据和优先事项:全球百日咳倡议的最新发现。
2023年,全球百日咳倡议在10个拉丁美洲国家召开会议,评估百日咳负担和疫苗接种政策。虽然百日咳在代表国家是一种法定疾病,但疾病认识不足,老年人认识不足,实验室能力和供应有限,对收集可靠的流行病学数据构成挑战。所有10个国家的婴儿均接受3剂初级系列疫苗,随后接受≥2剂加强疫苗。除巴拉圭和委内瑞拉外,代表国家的政府建议或授权在怀孕期间接种疫苗;然而,覆盖率仍然不够理想。应教育卫生保健提供者和公众,使其了解母亲和其他接触者如何可能成为百日咳博德泰拉(将疾病传播给易感婴儿)的无症状携带者,以及青少年和成人百日咳的潜在独特表现。拉丁美洲的百日咳负担可通过改善初级系列疫苗接种覆盖率、增加妊娠期疫苗接种和实行成人普遍疫苗接种来减轻。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Open Forum Infectious Diseases
Open Forum Infectious Diseases Medicine-Neurology (clinical)
CiteScore
6.70
自引率
4.80%
发文量
630
审稿时长
9 weeks
期刊介绍: Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.
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