Lesioning Through a Directional Deep Brain Stimulation Lead in the Subthalamic Nucleus.

IF 2.5 Q2 CLINICAL NEUROLOGY
Tremor and Other Hyperkinetic Movements Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI:10.5334/tohm.993
Alfonso Enrique Martinez Nunez, Dorian M Kusyk, Joshua K Wong, Michael S Okun, Justin D Hilliard
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引用次数: 0

Abstract

Clinical vignette: A 59-year-old woman with a previous subthalamic nucleus deep brain stimulation (DBS) implanted for Parkinson's disease developed a hardware related infection.

Clinical dilemma: Wound dehiscence and infection developed and necessitated removal of the DBS system. The patient experienced excellent therapeutic benefit from her DBS and expressed concern about device removal.

Clinical solution: The patient was offered the option of a lesioning procedure which could be performed during hardware explantation. An operative procedure was conducted where the intracranial DBS lead was connected to a radiofrequency system in a deliberate effort to create a targeted subthalamotomy through the existing DBS lead. A multilevel lesion was generated using the contacts on the directional DBS lead. Following the lesion the DBS lead and hardware were removed.

Gap in knowledge: Creating a lesion through a DBS lead using radiofrequency ablation is a therapeutic option for patients not interested in later re-implantation or for those with a history of multiple DBS related infections. Lesioning through segmented leads introduces more complexity into the procedure.

通过丘脑下核定向深部脑刺激引起的损伤。
临床简介:一名59岁的女性,先前接受了丘脑下核深部脑刺激(DBS)植入治疗帕金森病,后来发生了硬件相关感染。临床困境:伤口裂开和感染的发展,需要去除DBS系统。患者从DBS中获得了极好的治疗效果,并表达了对器械移除的担忧。临床解决方案:患者可以选择在硬体外植术中进行病变手术。手术过程中,颅内DBS导联连接到射频系统,有意通过现有的DBS导联创建一个目标丘脑下切开术。使用定向DBS导联上的触点产生多级病变。病变后取出DBS导联和硬体。知识空白:通过DBS导联使用射频消融术制造病变是对以后再植入不感兴趣的患者或有多次DBS相关感染史的患者的治疗选择。通过分段导联的病变引入了更复杂的程序。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.00
自引率
4.50%
发文量
31
审稿时长
6 weeks
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