Isolated Muscular NK/T Cell Lymphoma: A Rare Presentation of Post-Transplant Lymphoproliferative Disorders.

IF 0.4 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Indian Journal of Nuclear Medicine Pub Date : 2024-11-01 Epub Date: 2025-03-20 DOI:10.4103/ijnm.ijnm_108_24

Srishti Srivastava, Parag Jilhare, Aftab Hasan Nazar, Manish Ora, Sanjay Gambhir

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引用次数: 0

Abstract

Posttransplant lymphoproliferative disorders (PTLDs) represent a spectrum of malignancies occurring in transplant recipients under immunosuppression, often linked with Epstein-Barr Virus infection. PTLD has a varied presentation, and isolated muscular involvement is infrequent. Here, we present the case of a 47-year-old female renal transplant recipient presenting with acute left knee joint swelling, initially suggestive of an infective or inflammatory etiology. Biopsy revealed high-grade non-Hodgkin lymphoma of natural killer/T-cell lymphoma. F-18 Fluorodeoxyglucose positron emission tomography-computed tomography scan revealed metabolically active soft tissue mass lesions isolated to thigh muscles. The patient was on a modified chemotherapy regimen tailored to accommodate renal function. This case underscores the necessity for heightened vigilance in diagnosing PTLD, particularly considering its atypical presentations.

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孤立性肌肉NK/T细胞淋巴瘤：移植后淋巴细胞增生性疾病的罕见表现。

移植后淋巴细胞增生性疾病（ptld）是免疫抑制移植受者发生的一系列恶性肿瘤，通常与eb病毒感染有关。PTLD有多种表现，孤立的肌肉受累并不常见。在这里，我们提出的情况下，47岁的女性肾移植受者提出急性左膝关节肿胀，最初提示感染或炎症的病因。活检显示高级别非霍奇金淋巴瘤的自然杀伤/ t细胞淋巴瘤。F-18氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描显示代谢活跃的软组织病变孤立于大腿肌肉。病人正在接受一种改良的化疗方案，以适应肾功能。本病例强调了在诊断PTLD时提高警惕的必要性，特别是考虑到其非典型表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

0.70

自引率

0.00%

发文量